Evidence map›Paper›PMID 36909556›Full record

ArticlebioRxiv : the preprint server for biology2023

Comparative Features of Calretinin, Calbindin and Parvalbumin Expressing Interneurons in Mouse and Monkey Primary Visual and Frontal Cortices.

Maria Medalla, Bingxin Mo, Rakin Nasar, Yuxin Zhou, Junwoo Park, Jennifer I Luebke

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria MedallaDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Bingxin MoDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Rakin NasarDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Yuxin ZhouDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Junwoo ParkDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Jennifer I LuebkeDepartment of Anatomy & Neurobiology, Boston University Chobanian & Avedisian School of Medicine, 72 East Concord St. L10, Boston MA 02118.
Boston University · US

Funding

Circuit structure and dynamics in prefrontal-limbic networksR01MH116008 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Maria Medalla · 2019 to 2026
$3.7M
Mechanisms of Age-related Cognitive Decline in the Rhesus MonkeyR01AG059028 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOF, PATRICK R, LUEBKE, JENNIFER I · 2018 to 2022
$3.5M
CRCNS: Age-related changes to cortical dynamics underlying working memoryR01AG071230 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LUEBKE, JENNIFER I · 2020 to 2022
$553k
NIA NIH HHS R01 AG059028NIA NIH HHS R01 AG071230NIMH NIH HHS R01 MH116008
6 · The paper itself

Abstract

Much is known about differences in pyramidal cells across cortical areas and species, but studies of interneurons have focused on comparisons within single cortical areas and/or species. Here we quantified the distribution and somato-dendritic morphology of interneurons expressing one or more of the calcium binding proteins (CaBPs) calretinin (CR), calbindin (CB) and/or parvalbumin (PV) in mouse ( Key Points: Somato-dendritic morphology of distinct interneurons did not substantially scale and vary across areas and species- differences were mainly dependent on CaBP expression.Cortical diversity in inhibitory function across areas and species is thus likely to be derived from differential laminar distribution and densities of distinct interneuron subclasses.In contrast to pyramidal cells which differ widely in distribution and morphology across areas and species, the features of interneurons appears to be relatively more conserved across areas and species.

Identifiers

PMID36909556
PMCPMC10002648
OpenAlexW4322625855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.