Evidence map›Paper›PMID 36909541›Full record

ArticlebioRxiv : the preprint server for biology2023

Integrated Stress Response signaling acts as a metabolic sensor in fat tissues to regulate oocyte maturation and ovulation.

Lydia Grmai, Manuel Michaca, Emily Lackner, Narayanan Nampoothiri V P, Deepika Vasudevan

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manuel Michaca
Emily Lackner
Narayanan Nampoothiri V P
Deepika VasudevanORCID 0000-0003-1930-3549
University of Pittsburgh · US

Funding

Interinstitutional Program in Cell and Molecular Biology: A Graduate Training Path to Promote Traditional and Non-Traditional Professional OutcomesT32GM133353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRODSKY, JEFFREY L., MURRAY, SANDRA ANN · 2020 to 2024
$1.5M
ER stress-induced translational regulation in retinal degenerationR00EY029013 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASUDEVAN, DEEPIKA · 2021 to 2023
$724k
Stress response signaling as a metabolic sensor in reproductionK99GM149982 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRMAI, LYDIA · 2023 to 2024
$198k
NEI NIH HHS R00 EY029013NIGMS NIH HHS K99 GM149982NIGMS NIH HHS T32 GM133353
6 · The paper itself

Abstract

Reproduction is an energy-intensive process requiring systemic coordination. However, the inter-organ signaling mechanisms that relay nutrient status to modulate reproductive output are poorly understood. Here, we use

Identifiers

PMID36909541
PMCPMC10002630
OpenAlexW4322622228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.