Evidence map›Paper›PMID 36909523›Full record

ArticlebioRxiv : the preprint server for biology2023

Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells.

Audrey Miller Williams, Sally Horne-Badovinac

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Audrey Miller WilliamsDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA.
Sally Horne-BadovinacDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA.
University of Chicago · US

Funding

Training Program in Developmental BiologyT32HD055164 · NICHD · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac, Paschalis Kratsios · 2008 to 2026
$3.6M
Mechanisms of epithelial migration and basement membrane assemblyR35GM148285 · NIGMS · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac · 2023 to 2026
$2.4M
Mechanisms that Coordinate Cellular Movements for Epithelial MigrationR01GM126047 · NIGMS · UNIVERSITY OF CHICAGO · PI HORNE-BADOVINAC, SALLY · 2018 to 2021
$1.6M
NICHD NIH HHS T32 HD055164NIGMS NIH HHS R01 GM126047NIGMS NIH HHS R35 GM148285
6 · The paper itself

Abstract

Migrating epithelial cells globally align their migration machinery to achieve tissue-level movement. Biochemical signaling across leading-trailing cell-cell interfaces can promote this alignment by partitioning migratory behaviors like protrusion and retraction to opposite sides of the interface. However, how the necessary signaling proteins become organized at this site is poorly understood. The follicular epithelial cells of

Identifiers

PMID36909523
PMCPMC10002635
OpenAlexW4323038261

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.