Evidence map›Paper›PMID 36909515›Full record

ArticlebioRxiv : the preprint server for biology2023

Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses.

Ian N Boys, Alex G Johnson, Meghan Quinlan, Philip J Kranzusch, Nels C Elde

Open access · greenFull text readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ian N BoysDepartment of Human Genetics, University of Utah, Salt Lake City, Utah, 84112 USA.
Alex G JohnsonDepartment of Microbiology, Harvard Medical School, Boston, MA, 02115, USA.
Meghan QuinlanDepartment of Human Genetics, University of Utah, Salt Lake City, Utah, 84112 USA.
Philip J KranzuschDepartment of Microbiology, Harvard Medical School, Boston, MA, 02115, USA.
Nels C EldeDepartment of Human Genetics, University of Utah, Salt Lake City, Utah, 84112 USA.
Howard Hughes Medical Institute · USHarvard University · US

Funding

Unlocking evolutionarily latent immune functions for treating diseaseR01CA260414 · NCI · UNIVERSITY OF UTAH · PI BASS, BRENDA L., ELDE, NELS C. · 2020 to 2024
$5.8M
Evolutionary innovations from host-microbe interactionsR35GM134936 · NIGMS · UNIVERSITY OF UTAH · PI ELDE, NELS C. · 2020 to 2024
$1.7M
NCI NIH HHS R01 CA260414NIGMS NIH HHS R35 GM134936
6 · The paper itself

Abstract

Viruses acquire host genes via horizontal gene transfer and can express them to manipulate host biology during infections. Some viral and host homologs retain sequence identity, but evolutionary divergence can obscure host origins. We used structural modeling to compare vaccinia virus proteins with metazoan proteomes. We identified vaccinia

Identifiers

PMID36909515
PMCPMC10002665
OpenAlexW4322489152

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read69
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.