Evidence map›Paper›PMID 36909513›Full record

ArticlebioRxiv : the preprint server for biology2023

Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the

Najeeb U Siddiqui, Angelo Karaiskakis, Aaron L Goldman, Whitby V I Eagle, Craig A Smibert, Elizabeth R Gavis, Howard D Lipshitz

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Najeeb U SiddiquiDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Angelo KaraiskakisDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Aaron L GoldmanDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Whitby V I EagleDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Craig A SmibertDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Elizabeth R GavisDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Howard D LipshitzDepartment of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
University of Toronto · CAPrinceton University · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007388 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 1985 to 2022
$27.4M
Mechanism of RNA Localization in Drosophila DevelopmentR01GM067758 · NIGMS · PRINCETON UNIVERSITY · PI GAVIS, ELIZABETH R · 2004 to 2017
$5.3M
Translational Regulation of Patterning in DrosphilaR01GM061107 · NIGMS · PRINCETON UNIVERSITY · PI GAVIS, ELIZABETH R · 2001 to 2017
$5.2M
NIGMS NIH HHS R01 GM061107NIGMS NIH HHS R01 GM067758NIGMS NIH HHS T32 GM007388
6 · The paper itself

Abstract

During Drosophila oogenesis, the Oskar (OSK) RNA-binding protein (RBP) determines the amount of germ plasm that assembles at the posterior pole of the oocyte. Here we identify the mechanisms that regulate the

Identifiers

PMID36909513
PMCPMC10002672
OpenAlexW4322488342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.