Evidence map›Paper›PMID 36909484›Full record

ArticleResearch square2023

Babesia divergens egress from host cells is orchestrated by essential and druggable kinases and proteases.

Brendan Elsworth, Caroline Keroack, Yasaman Rezvani, Aditya Paul, Keare Barazorda, Jacob Tennessen, Samantha Sack, Cristina Moreira, Marc-Jan Gubbels, Marvin Meyers and 2 more

Open access · greenFull text readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Brendan ElsworthHarvard T.H. Chan School of Public Health.
Caroline KeroackHarvard T.H. Chan School of Public Health.
Yasaman RezvaniUniversity of Massachusetts Boston.
Aditya PaulHarvard T.H. Chan School of Public Health.ORCID 0000-0003-4123-7410
Keare BarazordaHarvard T.H. Chan School of Public Health.
Jacob TennessenHarvard T.H. Chan School of Public Health.
Samantha SackHarvard T.H. Chan School of Public Health.
Cristina MoreiraHarvard T.H. Chan School of Public Health.
Marc-Jan GubbelsBoston College.
Marvin MeyersSaint Louis University.
Kourosh ZarringhalamUniversity of Massachusetts Boston.
Manoj DuraisinghHarvard T.H. Chan School of Public Health.ORCID 0000-0001-8534-5515
Harvard University · USUniversity of Massachusetts Boston · USBoston College · USUCLouvain Saint-Louis Brussels · BE

Funding

Comparative systems biology of apicomplexan cell divisionR01AI167570 · NIAID · BOSTON COLLEGE · PI Manoj T Duraisingh, Marc-Jan Gubbels · 2022 to 2026
$6.5M
Dissecting transcriptional mechanisms underlying Toxoplasma stage transition through in vitro evolutionR21AI150090 · NIAID · BOSTON COLLEGE · PI GUBBELS, MARC-JAN, ZARRINGHALAM, KOUROSH · 2020 to 2021
$441k
Developing comparative chemical genomics and genetic validation tools for Babesia spp.R21AI153945 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI DURAISINGH, MANOJ T · 2020 to 2021
$439k
NIAID NIH HHS R01 AI167570NIAID NIH HHS R21 AI150090NIAID NIH HHS R21 AI153945
6 · The paper itself

Abstract

Apicomplexan egress from host cells is fundamental to the spread of infection and is poorly characterized in

Identifiers

PMID36909484
PMCPMC10002801
OpenAlexW4322622302

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read59
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.