Evidence map›Paper›PMID 36909214›Full record

ArticlePerspectives in clinical research

Evaluation of medical adherence, adverse drug reactions, and quality of life in post tubercular obstructive airway disease.

Vinita Awasthi, Sarvesh Singh, Narendra Kumar, Manoj Kumar, Amod Kumar Sachan, Rajiv Garg, Rahul Kumar

Abstract read
In one paragraph

Article in Perspectives in clinical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. The Global Landscape ofPathogens (Basel, Switzerland) · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vinita AwasthiDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sarvesh SinghDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Narendra KumarDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Manoj KumarDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Amod Kumar SachanDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.
Rajiv GargDepartment of Respiratory Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
Rahul KumarDepartment of Pharmacology and Therapeutics, King George's Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increasing incidence of tuberculosis is intensifying the posttubercular obstructive airway disease (PTOAD) in developing countries. Currently, there are no standard treatment guidelines for the management of PTOAD patients. The present study aims to evaluate the prescribing pattern, adherence, adverse drug reactions (ADRs), and quality of life (QoL) in PTOAD patients. Materials and Methods: A prospective observational study was conducted to evaluate the prescriptions of PTOAD patients, estimating the medical adherence using Morisky 8-Item Medication Adherence Questionnaire, assessing ADRs using Hartwig's Severity Assessment Scale and assessing QoL using St. George's respiratory Questionnaire. Chi-square test, analysis of variance, paired Results: A total of 94 prescriptions of PTOAD were analyzed. Inhaled long-acting muscarinic antagonist was prescribed to 31.9% of patients. The most common inhaled fixed dose combination was long-acting beta-2 agonist with corticosteroid, prescribed to 52.1% of patients. At final follow-up, maximum percentage of patients were found to be highly adherent, i.e. 56.4%. Overall, 34% of patients have complained about mild category of ADRs. A significant improvement in QoL was observed. At baseline, mean forced expiratory volume in 1 (FEV Conclusion: Bronchodilators are the mainstay of treatment of PTOAD patients, since both the QoL and FEV1 were improved with treatments. However, to have good treatment outcome, strict adherence along with safety of the medications must be assured.

Indexed as

adherencebronchodilatorscorticosteroidsobstructiontuberculosis

Identifiers

PMID36909214
PMCPMC10003586

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.