Evidence map›Paper›PMID 36908967›Full record

ArticleChemical science2023

Confinement effect on hydrolysis in small lipid vesicles.

Ben Woods, Katherine C Thompson, Nicolas Szita, Shu Chen, Lilia Milanesi, Salvador Tomas

Abstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ben WoodsDepartment of Biological Sciences and Institute of Structural and Molecular Biology, Birkbeck, University of London Malet Street London WC1E 7HX UK.
Katherine C ThompsonDepartment of Biological Sciences and Institute of Structural and Molecular Biology, Birkbeck, University of London Malet Street London WC1E 7HX UK.ORCID https://orcid.org/0000-0002-9293-610X
Nicolas SzitaDepartment of Biochemical Engineering, University College London, Bernard Katz Building Gordon Street London WC1H 0AH UK.
Shu ChenDepartment of Biological Sciences and Institute of Structural and Molecular Biology, Birkbeck, University of London Malet Street London WC1E 7HX UK.
Lilia MilanesiDepartment of Chemistry, University of the Balearic Islands Ctra. de Valldemossa, Km 7.5 07122 Palma de Mallorca Spain salvador.tomas@uib.es.
Salvador TomasDepartment of Biological Sciences and Institute of Structural and Molecular Biology, Birkbeck, University of London Malet Street London WC1E 7HX UK.ORCID https://orcid.org/0000-0002-3622-9101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In living organisms most chemical reactions take place within the confines of lipid-membrane bound compartments, while confinement within the bounds of a lipid membrane is thought to be a key step in abiogenesis. In previous work we demonstrated that confinement in the aqueous cavity of a lipid vesicle affords protection against hydrolysis, a phenomenon that we term here confinement effect (

Identifiers

PMID36908967
PMCPMC9993861

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.