Evidence map›Paper›PMID 36908713›Full record

ArticleFrontiers in human neuroscience2023

Case report: Backward gait training combined with gait-synchronized cerebellar transcranial alternating current stimulation in progressive supranuclear palsy.

Atsushi Shima, Kazuki Tanaka, Akari Ogawa, Erika Omae, Tomoaki Miyake, Yui Nagamori, Yusuke Miyata, Koji Ohata, Yumie Ono, Tatsuya Mima and 2 more

Abstract readCase Reports
In one paragraph

Article in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Atsushi ShimaDepartment of Regenerative Systems Neuroscience, Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kazuki TanakaDepartment of Regenerative Systems Neuroscience, Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akari OgawaDepartment of Regenerative Systems Neuroscience, Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Erika OmaeDivision of Neurobiology and Physiology, Department of Neuroscience, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tomoaki MiyakeDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yui NagamoriDepartment of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yusuke MiyataDepartment of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Koji OhataDepartment of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yumie OnoDepartment of Electronics and Bioinformatics, Meiji University, Tokyo, Kanagawa, Japan.
Tatsuya MimaThe Graduate School of Core Ethics and Frontier Sciences, Ritsumeikan University, Kyoto, Japan.
Ryosuke TakahashiDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Satoko KoganemaruDepartment of Regenerative Systems Neuroscience, Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy (PSP) is characterized by recurrent falls caused by postural instability, and a backward gait is considered beneficial for postural instability. Furthermore, a recent approach for rehabilitation combined with gait-oriented synchronized stimulation using non-invasive transcranial patterned stimulation could be promising for balance function. Here, we present a case of PSP with backward gait training combined with gait-synchronized transcranial alternating current stimulation (tACS). A 70-year-old woman with PSP-Richardson's syndrome underwent backward gait training combined with synchronized cerebellar tACS. Initially, she underwent short-term intervention with combined training of backward gait with synchronized cerebellar tACS, asynchronized, or sham stimulation according to the N-of-1 study design. Synchronized tACS training demonstrated a decrease in postural instability, whereas asynchronized or sham stimulation did not. The additional long-term interventions of combined backward gait training with synchronized cerebellar tACS demonstrated further decrease in postural instability with improvements in gait speed, balance function, and fall-related self-efficacy in daily life. The present case describes a novel approach for motor symptoms in a patient with PSP. Backward gait training with synchronized cerebellar tACS may be a promising therapeutic approach.

Indexed as

backward gaitcerebellumentrainmentnon-invasive brain stimulation (NIBS)Parkinsonismprogressive supranuclear palsyrehabilitationtranscranial alternating current stimulation

Identifiers

PMID36908713
PMCPMC9992165

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.