Evidence map›Paper›PMID 36908449›Full record

ArticleFrontiers in public health2023

Online HIV prophylaxis delivery: Protocol for the ePrEP Kenya pilot study.

Catherine Kiptinness, Paulami Naik, Nicholas Thuo, Rachel C Malen, Julia C Dettinger, Jillian Pintye, Maeve Rafferty, Edwin Jomo, Nicky Nyamasyo, Tony Wood and 9 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Preventing HIV in women in Africa.Nature medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Catherine KiptinnessPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Paulami NaikDepartment of Global Health, University of Washington, Seattle, WA, United States.
Nicholas ThuoPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Rachel C MalenPublic Health Science Division, Fred Hutchinson Cancer Center, Seattle, WA, United States.
Julia C DettingerDepartment of Global Health, University of Washington, Seattle, WA, United States.
Jillian PintyeDepartment of Biobehavioral Nursing and Health Informatics, Seattle, WA, United States.
Maeve RaffertyMYDAWA, Nairobi, Kenya.
Edwin JomoMYDAWA, Nairobi, Kenya.
Nicky NyamasyoMYDAWA, Nairobi, Kenya.
Tony WoodMYDAWA, Nairobi, Kenya.
Paul IsabelliAudere, Seattle, WA, United States.
Sarah MorrisAudere, Seattle, WA, United States.
David HatteryAudere, Seattle, WA, United States.
Andy StergachisDepartment of Global Health, University of Washington, Seattle, WA, United States.
Daniel WereJhpiego, Nairobi, Kenya.
Monisha SharmaDepartment of Global Health, University of Washington, Seattle, WA, United States.
Kenneth NgureSchool of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Melissa Latigo MugambiDepartment of Global Health, University of Washington, Seattle, WA, United States.
Katrina F OrtbladPublic Health Science Division, Fred Hutchinson Cancer Center, Seattle, WA, United States.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Peer PrEP referral + HIV self-test for PrEP initiation among young Kenyan womenR00MH121166 · NIMH · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ORTBLAD, KATRINA FRANCES · 2021 to 2024
$866k
The design and evaluation of strategies to implement HIV prevention interventions for pregnant women in community pharmacy settingsK01MH122326 · NIMH · UNIVERSITY OF WASHINGTON · PI MUGAMBI, MELISSA · 2021 to 2024
$582k
Peer PrEP referral + HIV self-test for PrEP initiation among young Kenyan womenK99MH121166 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2020 to 2020
$122k
NIAID NIH HHS P30 AI027757NIMH NIH HHS K01 MH122326NIMH NIH HHS K99 MH121166NIMH NIH HHS R00 MH121166
6 · The paper itself

Abstract

Background: Online pharmacies in Kenya provide sexual and reproductive health products (e.g., HIV self-testing, contraception) and could be leveraged to increase the reach of HIV pre-exposure and post-exposure prophylaxis (PrEP/PEP) to populations who do not frequently attend health facilities. To date, evidence is limited for operationalizing online PrEP/PEP delivery and the type of populations reached with this differential service delivery model. Methods: The ePrEP Kenya Pilot will deliver daily oral PrEP and PEP Discussion: Establishing pathways to increase PrEP and PEP access is crucial to help curb new HIV infections in settings with high HIV prevalence. The findings from this study will provide evidence on the implementation of online pharmacy PrEP and PEP service delivery that can help inform guidelines in Kenya and similar settings.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisHumansKenyaPilot Projectsdifferentiated service deliveryHIV preventionimplementation scienceKenyaPEPPrEPtelehealth

Identifiers

PMID36908449
PMCPMC9998902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.