Evidence map›Paper›PMID 36907943›Full record

SynthesisWorld journal of urology2023

Kidney transplantation from elderly donors (> 70 years): a systematic review.

Benoit Mesnard, Angelo Territo, Riccardo Campi, Vital Hevia, Iulia Andras, Alberto Piana, Alessio Pecoraro, Romain Boissier, Thomas Prudhomme, EAU-Young Academic Urologist (YAU) group of Kidney Transplantation

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Donor Characteristics Associated With Graft Loss and Delayed Graft Function in Very-Aged Kidney Donors: An Observational Multicentric Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Observational
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benoit Mesnard *Department of Urology, Nantes Université, CHU Nantes, Nantes, France.
Angelo Territo *Uro-Oncology and Kidney Transplant Unit, Department of Urology at "Fundació Puigvert" Hospital, Autonoma University of Barcelona, Barcelona, Spain.
Riccardo CampiDepartment of Urology, Florence University Hospital, Florence, Italy.
Vital HeviaDepartment of Urology, University Hospital Ramón y Cajal, Madrid, Spain.
Iulia AndrasDepartment of Urology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Alberto PianaDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy.
Alessio PecoraroDepartment of Urology, Florence University Hospital, Florence, Italy.
Romain BoissierDepartment of Urology, La Conception University Hospital, Marseille, France.
Thomas PrudhommeDepartment of Urology and Kidney Transplantation, Toulouse University Hospital, TSA 50032 Rangueil Hospital, 31059, Toulouse Cedex 9, France. prudhomme.t@chu-toulouse.fr.ORCID http://orcid.org/0000-0003-3601-9339
EAU-Young Academic Urologist (YAU) group of Kidney Transplantation

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe incidence of kidney transplants from elderly donors over 70 years of age has increased significantly over the past 10 years to reach 20% of available kidney graft in some European countries. However, there is little data available on the outcomes of transplants from these donors. We performed a systematic review to evaluate the outcomes of transplantation from donors over 70 years of age.

methodsA systematic review was performed according to preferred reporting items for systematic reviews and meta-analyses. Medline, Embase, and Cochrane databases were searched to identify all studies reporting outcomes on kidney transplants from donors over 70 years. Due to the heterogeneity of the studies, a meta-analysis could not be performed.

resultsA total of 29,765 patients in 27 studies were included. The mean donors age was 74.79 years, and proportion of kidney graft from women was 53.54%. The estimated 1- and 5-year kidney death-censored graft survivals from donors > 70 years old were, respectively, 85.95 and 80.27%, and the patient survivals were 90.88 and 71.29%. The occurrence of delayed graft function was 41.75%, and primary non-function was 4.67%. Estimated graft function at 1 and 5 years was 36 and 38 mL/min/1.73 m

conclusionsElderly donors appear to be a reliable source of grafts. However, these transplants are associated with a high rate of delayed graft function without repercussion on long-term graft survival. Allocation strategy to elderly recipients is the main factor of decreased recipient survival.

Indexed as

Kidney TransplantationAgedAged, 80 and overAge FactorsDelayed Graft FunctionFemaleGraft SurvivalHumansKidneyTissue DonorsAged, 70 and overDonor selectionGraft survivalKidney transplantation

Identifiers

PMID36907943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.