Evidence map›Paper›PMID 36907855›Full record

ArticleBMC pulmonary medicine2023

Post-COVID dyspnea: prevalence, predictors, and outcomes in a longitudinal, prospective cohort.

Japnam S Grewal, Christopher Carlsten, James C Johnston, Aditi S Shah, Alyson W Wong, Christopher J Ryerson

Open access · goldFull text read
In one paragraph

Article in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Assessment and management of post-COVID-19 pulmonary complications: a rapid review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Review
  6. Article
  7. Virtual Pet-Assisted Therapy to Alleviate Symptoms of Long COVID: A Prospective Pilot Interventional Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Long COVID Symptom Management Through Self-Care and Nonprescription Treatment Options: A Narrative Review.International journal of environmental research and public health · 2025
    Review
  12. Article
  13. Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Japnam S GrewalDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Christopher CarlstenDepartment of Medicine, University of British Columbia, Vancouver, Canada.
James C JohnstonDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Aditi S ShahDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Alyson W WongDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Christopher J RyersonDepartment of Medicine, University of British Columbia, Vancouver, Canada. Chris.Ryerson@hli.ubc.ca.
University of British Columbia · CASt. Paul's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pathophysiology, evolution, and associated outcomes of post-COVID dyspnea remain unknown. The aim of this study was to determine the prevalence, severity, and predictors of dyspnea 12 months following hospitalization for COVID-19, and to describe the respiratory, cardiac, and patient-reported outcomes in patients with post-COVID dyspnea.

methodsWe enrolled a prospective cohort of all adult patients admitted to 2 academic hospitals in Vancouver, Canada with PCR-confirmed SARS-CoV-2 during the first wave of COVID between March and June 2020. Dyspnea was measured 3, 6, and 12 months after initial symptom onset using the University of California San Diego Shortness of Breath Questionnaire.

resultsA total of 76 patients were included. Clinically meaningful dyspnea (baseline score > 10 points) was present in 49% of patients at 3 months and 46% at 12 months following COVID-19. Between 3 and 12 months post-COVID-19, 24% patients had a clinically meaningful worsening in their dyspnea, 49% had no meaningful change, and 28% had a clinically meaningful improvement in their dyspnea. There was worse sleep, mood, quality of life, and frailty in patients with clinically meaningful dyspnea at 12 months post-COVID infection compared to patients without dyspnea. There was no difference in PFT findings, troponin, or BNP comparing patients with and without clinically meaningful dyspnea at 12 months. Severity of dyspnea and depressive symptoms at 3 months predicted severity of dyspnea at 12 months.

conclusionsPost-COVID dyspnea is common, persistent, and negatively impacts quality of life. Mood abnormalities may play a causative role in post-COVID dyspnea in addition to potential cardiorespiratory abnormalities. Dyspnea and depression at initial follow-up predict longer-term post-COVID dyspnea, emphasizing that standardized dyspnea and mood assessment following COVID-19 may identify patients at high risk of post-COVID dyspnea and facilitating early and effective management.

Indexed as

COVID-19Quality of LifeAdultDyspneaHumansPrevalenceProspective StudiesSARS-CoV-2COVID-19DyspneaOutcomesPatientPredictors

Identifiers

PMID36907855
PMCPMC10008721
OpenAlexW4324020908

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read25
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.