Evidence map›Paper›PMID 36907736›Full record

Observational studyVaccine2023

The mediating effect of health literacy on COVID-19 vaccine confidence among a diverse sample of urban adults in Boston and Chicago.

Emily E Hurstak, Michael K Paasche-Orlow, Elizabeth A Hahn, Lori E Henault, Michelle A Taddeo, Patricia I Moreno, Claire Weaver, Melissa Marquez, Eloisa Serrano, Jessica Thomas and 1 more

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in Vaccine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03584490 (Reducing Assessment Barriers for Patients With Low Health Literacy), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03584490 nacompletednot on this map

Reducing Assessment Barriers for Patients With Low Health Literacy

TypeinterventionalSponsorNorthwestern UniversityRan2018 to 2023Enrolled729ConditionsHealth LiteracyArmsComputerized Talking Touchscreen, Phone Administration of Questionnaires
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Review
  6. The still unexplored mediating role of vaccine literacy.Human vaccines & immunotherapeutics · 2024
    Article
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  8. Review
  9. Article
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  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Emily E HurstakSection of General Internal Medicine, Boston University School of Medicine, 801 Massachusetts Avenue, Boston, MA 02118, USA. Electronic address: Emily.hurstak@bmc.org.
Michael K Paasche-OrlowDepartment of Medicine, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA. Electronic address: mpo@tuftsmedicalcenter.org.
Elizabeth A HahnDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: e-hahn@northwestern.edu.
Lori E HenaultSection of General Internal Medicine, Boston University School of Medicine, 801 Massachusetts Avenue, Boston, MA 02118, USA. Electronic address: Lori.henault@bmc.org.
Michelle A TaddeoDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: Michelle.taddeo@northwestern.edu.
Patricia I MorenoDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL 33136, USA. Electronic address: Patricia.moreno@miami.edu.
Claire WeaverDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: claireweaver2023@u.northwestern.edu.
Melissa MarquezDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: melissa.marquez@northwestern.edu.
Eloisa SerranoDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: Eloisa.serrano@northwestern.edu.
Jessica ThomasDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: jessica.thomas@northwestern.edu.
James W GriffithDepartment of Medical Social Sciences Northwestern Feinberg School of Medicine 625 N. Michigan Ave., Chicago, IL 60611, USA. Electronic address: j-griffith@northwestern.edu.
Northwestern University · USBoston University · USTufts Medical Center · USUniversity of Miami · US

Funding

Reducing Assessment Barriers for Patients with Low LiteracyR01MD010440 · NIMHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GRIFFITH, JAMES WILLIAM, PAASCHE-ORLOW, MICHAEL · 2017 to 2021
$4.6M
Patient Activation and Palliative Care among Hispanics/Latinos with Metastatic CancerK01CA258955 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MORENO, PATRICIA INGRID · 2021 to 2025
$834k
NCI NIH HHS K01 CA258955NIMHD NIH HHS R01 MD010440
6 · The paper itself

Abstract

backgroundA high rate of COVID-19 vaccination is critical to reduce morbidity and mortality related to infection and to control the COVID-19 pandemic. Understanding the factors that influence vaccine confidence can inform policies and programs aimed at vaccine promotion. We examined the impact of health literacy on COVID-19 vaccine confidence among a diverse sample of adults living in two major metropolitan areas.

methodsQuestionnaire data from adults participating in an observational study conducted in Boston and Chicago from September 2018 through March 2021 were examined using path analyses to determine whether health literacy mediates the relationship between demographic variables and vaccine confidence, as measured by an adapted Vaccine Confidence Index (aVCI).

resultsParticipants (N = 273) were on average 49 years old, 63 % female, 4 % non-Hispanic Asian, 25 % Hispanic, 30 % non-Hispanic white, and 40 % non-Hispanic Black. Using non-Hispanic white and other race as the reference category, Black race and Hispanic ethnicity were associated with lower aVCI (-0.76, 95 % CI -1.00 to -0.50; -0.52, 95 % CI -0.80 to -0.27, total effects from a model excluding other covariates). Lower education was also associated with lower aVCI (using college or more as the reference, -0.73 for 12th grade or less, 95 % CI -0.93 to -0.47; -0.73 for some college/associate's/technical degree, 95 % CI -1.05 to -0.39). Health literacy partially mediated these effects for Black and Hispanic participants and those with lower education (indirect effects -0.19 and -0.19 for Black race and Hispanic ethnicity; 0.27 for 12th grade or less; -0.15 for some college/associate's/technical degree).

conclusionsLower levels of education, Black race, and Hispanic ethnicity were associated with lower scores on health literacy, which in turn were associated with lower vaccine confidence. Our findings suggest that efforts to improve health literacy may improve vaccine confidence, which in turn may improve vaccination rates and vaccine equity. CLINICAL TRIALS NUMBER: NCT03584490.

Indexed as

COVID-19COVID-19 VaccinesHealth LiteracyVaccinationAdultBlack or African AmericanBostonChicagoFemaleHispanic or LatinoHumansMaleMiddle AgedPandemicsWhiteCOVID-19 VaccinesCOVID-19Health disparitiesHealth literacySARS-CoV-2Vaccine acceptanceVaccine hesitancy

Identifiers

PMID36907736
PMCPMC9977617
OpenAlexW4322772608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.