Evidence map›Paper›PMID 36907594›Full record

ArticleKorean journal of radiology2023

Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension.

Yu-Sen Huang, Zheng-Wei Chen, Wen-Jeng Lee, Cho-Kai Wu, Ping-Hung Kuo, Hsao-Hsun Hsu, Shu-Yu Tang, Cheng-Hsuan Tsai, Mao-Yuan Su, Chi-Lun Ko and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yu-Sen HuangDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0003-4262-8712
Zheng-Wei ChenDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0001-7728-6674
Wen-Jeng LeeDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0003-3267-4811
Cho-Kai WuDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-3867-150X
Ping-Hung KuoDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0003-3756-3395
Hsao-Hsun HsuDepartment of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-0376-1206
Shu-Yu TangDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-4994-1923
Cheng-Hsuan TsaiDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0003-2859-5117
Mao-Yuan SuDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-6699-2298
Chi-Lun KoDepartments of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-4139-5892
Juey-Jen HwangDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0001-6437-0455
Yen-Hung LinDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0001-8153-1441
Yeun-Chung ChangDepartment of Medical Imaging, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. ycc5566@ntu.edu.tw.ORCID 0000-0001-9984-5713
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantitatively assess the pulmonary vasculature using non-contrast computed tomography (CT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) pre- and post-treatment and correlate CT-based parameters with right heart catheterization (RHC) hemodynamic and clinical parameters. MATERIALS AND

methodsA total of 30 patients with CTEPH (mean age, 57.9 years; 53% female) who received multimodal treatment, including riociguat for ≥ 16 weeks with or without balloon pulmonary angioplasty and underwent both non-contrast CT for pulmonary vasculature analysis and RHC pre- and post-treatment were included. The radiographic analysis included subpleural perfusion parameters, including blood volume in small vessels with a cross-sectional area ≤ 5 mm² (BV5) and total blood vessel volume (TBV) in the lungs. The RHC parameters included mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI). Clinical parameters included the World Health Organization (WHO) functional class and 6-minute walking distance (6MWD).

resultsThe number, area, and density of the subpleural small vessels increased after treatment by 35.7% (

conclusionNon-contrast CT measures could quantitatively assess changes in the pulmonary vasculature in response to treatment and were correlated with hemodynamic and clinical parameters.

Indexed as

Angioplasty, BalloonHypertension, PulmonaryPulmonary EmbolismChronic DiseaseFemaleHemodynamicsHumansLungMaleMiddle AgedPulmonary ArteryTomography, X-Ray ComputedChronic thromboembolic pulmonary hypertensionComputed tomographyHemodynamicsPulmonary vasculatureTreatment response

Identifiers

PMID36907594
PMCPMC10067691
OpenAlexW4324009136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.