Evidence map›Paper›PMID 36907397›Full record

ArticleThe Science of the total environment2023

Field trial assessing the antimicrobial decontamination efficacy of gaseous ozone in a public bus setting.

Erica Sena Neves, Cheng Teng Ng, Han Bin Pek, Vanessa Shi Li Goh, Roslinda Mohamed, Sheereen Osman, Yi Kai Ng, Sharain Abdul Kadir, Mohammad Nazeem, Alan She and 7 more

Open access · hybridAbstract read
In one paragraph

Article in The Science of the total environment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Advances in Ozone-Based Inactivation of SARS-CoV-2: An Updated Review.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Erica Sena NevesEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Cheng Teng NgEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Han Bin PekEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Vanessa Shi Li GohEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Roslinda MohamedEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Sheereen OsmanEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Yi Kai NgEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Sharain Abdul KadirEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Mohammad NazeemEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Alan SheVirestorm Pte. Ltd., 42E Penjuru Rd, Singapore; Singapore Heavy Engineering Pte. Ltd., 42B Penjuru Rd, Singapore.
Glenndle SimVirestorm Pte. Ltd., 42E Penjuru Rd, Singapore.
Joel AikEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore; Pre-hospital and Emergency Research Centre, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Lee Ching NgEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore.
Sophie OctaviaEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Zhanxiong FangEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Judith Chui Ching WongEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore.
Yin Xiang SetohEnvironmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore; Infectious Diseases Translational Research Programme (ID TRP), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Queensland, Australia. Electronic address: Setoh_Yin_Xiang@nea.gov.sg.
National Environment Agency · SGNanyang Technological University · SGUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) necessitated measures aimed at preventing the spread of SARS-CoV-2. To mitigate the risk of fomite-mediated transmission, environmental cleaning and disinfection regimes have been widely implemented. However, conventional cleaning approaches such as surface wipe downs can be laborious and more efficient and effective disinfecting technologies are needed. Gaseous ozone disinfection is one technology which has been shown to be effective in laboratory studies. Here, we evaluated its efficacy and feasibility in a public bus setting, using murine hepatitis virus (a related betacoronavirus surrogate) and the bacteria Staphylococcus aureus as test organisms. An optimal gaseous ozone regime resulted in a 3.65-log reduction of murine hepatitis virus and a 4.73-log reduction of S. aureus, and decontamination efficacy correlated with exposure duration and relative humidity in the application space. These findings demonstrated gaseous ozone disinfection in field settings which can be suitably translated to public and private fleets that share analogous characteristics.

Indexed as

Anti-Infective AgentsCOVID-19OzoneAnimalsDecontaminationDisinfectionHumansMicePandemicsSARS-CoV-2Staphylococcus aureusAnti-Infective AgentsOzoneAntimicrobial efficacyField trialGaseous ozoneMurine coronavirusStaphylococcus aureus

Identifiers

PMID36907397
PMCPMC9998280
OpenAlexW4323854333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.