Evidence map›Paper›PMID 36906984›Full record

ArticleClinical biomechanics (Bristol, Avon)2023

Radiographically successful periacetabular osteotomy does not achieve optimal contact mechanics in dysplastic hips.

Holly D Aitken, Aspen Miller, Dominic J L Rivas, Marcus Tatum, Robert W Westermann, Michael C Willey, Jessica E Goetz

Abstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Persistently elevated joint contact stress after periacetabular osteotomy is associated with joint failure at minimum 10-year follow-up.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Holly D AitkenDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
Aspen MillerDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
Dominic J L RivasDepartment of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA.
Marcus TatumDepartment of Industrial & Systems Engineering, University of Iowa, Iowa City, IA 52242, USA.
Robert W WestermannDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
Michael C WilleyDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA.
Jessica E GoetzDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, USA; Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA. Electronic address: jessica-goetz@uiowa.edu.

Funding

UI INITIATIVE FOR MINORITY STUDENT DEVELOPMENT PROGRAMR25GM058939 · NIGMS · UNIVERSITY OF IOWA · PI ADAMS-PHILLIPS, LORI C, FORBES, TORI · 1999 to 2021
$6.9M
NIGMS NIH HHS R25 GM058939
6 · The paper itself

Abstract

backgroundOptimal correction of hip dysplasia via periacetabular osteotomy may reduce osteoarthritis development by reducing damaging contact stress. The objective of this study was to computationally determine if patient-specific acetabular corrections that optimize contact mechanics can improve upon contact mechanics resulting from clinically successful, surgically achieved corrections.

methodsPreoperative and postoperative hip models were retrospectively created from CT scans of 20 dysplasia patients treated with periacetabular osteotomy. A digitally extracted acetabular fragment was computationally rotated in 2-degree increments around anteroposterior and oblique axes to simulate candidate acetabular reorientations. From discrete element analysis of each patient's set of candidate reorientation models, a mechanically optimal reorientation that minimized chronic contact stress exposure and a clinically optimal reorientation that balanced improving mechanics with surgically acceptable acetabular coverage angles was selected. Radiographic coverage, contact area, peak/mean contact stress, and peak/mean chronic exposure were compared between mechanically optimal, clinically optimal, and surgically achieved orientations.

findingsCompared to actual surgical corrections, computationally derived mechanically/clinically optimal reorientations had a median[IQR] 13[4-16]/8[3-12] degrees and 16[6-26]/10[3-16] degrees more lateral and anterior coverage, respectively. Mechanically/clinically optimal reorientations had 212[143-353]/217[111-280] mm

interpretationComputationally selected orientations achieved a greater mechanical improvement than surgically achieved corrections; however, many predicted corrections would be considered acetabular over-coverage. Identifying patient-specific corrections that balance optimizing mechanics with clinical constraints will be necessary to reduce the risk of osteoarthritis progression after periacetabular osteotomy.

Indexed as

Hip DislocationHip Dislocation, CongenitalOsteoarthritisAcetabulumHumansOsteotomyRetrospective StudiesTreatment OutcomeContact stressDiscrete element analysisHip dysplasiaOptimizationPeriacetabular osteotomy

Identifiers

PMID36906984
PMCPMC10122705

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.