Evidence map›Paper›PMID 36906638›Full record

ArticleScientific reports2023

A machine learning analysis of correlates of mortality among patients hospitalized with COVID-19.

Timothy B Baker, Wei-Yin Loh, Thomas M Piasecki, Daniel M Bolt, Stevens S Smith, Wendy S Slutske, Karen L Conner, Steven L Bernstein, Michael C Fiore

Open access · goldFull text read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Timothy B BakerCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA. tbb@ctri.medicine.wisc.edu.
Wei-Yin LohDepartment of Statistics, University of Wisconsin, Madison, WI, USA.
Thomas M PiaseckiCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
Daniel M BoltCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
Stevens S SmithCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
Wendy S SlutskeCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
Karen L ConnerCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
Steven L BernsteinDepartment of Emergency Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Michael C FioreCenter for Tobacco Research and Intervention (UW-CTRI), University of Wisconsin School of Medicine and Public Health, 1930 Monroe St #200, Madison, WI, 53711, USA.
University of Wisconsin–Madison · USDartmouth College · US

Funding

NCI NIH HHS CRDF Award #66590
6 · The paper itself

Abstract

It is vital to determine how patient characteristics that precede COVID-19 illness relate to COVID-19 mortality. This is a retrospective cohort study of patients hospitalized with COVID-19 across 21 healthcare systems in the US. All patients (N = 145,944) had COVID-19 diagnoses and/or positive PCR tests and completed their hospital stays from February 1, 2020 through January 31, 2022. Machine learning analyses revealed that age, hypertension, insurance status, and healthcare system (hospital site) were especially predictive of mortality across the full sample. However, multiple variables were especially predictive in subgroups of patients. The nested effects of risk factors such as age, hypertension, vaccination, site, and race accounted for large differences in mortality likelihood with rates ranging from about 2-30%. Subgroups of patients are at heightened risk of COVID-19 mortality due to combinations of preadmission risk factors; a finding of potential relevance to outreach and preventive actions.

Indexed as

COVID-19HypertensionHospitalizationHospital MortalityHumansMachine LearningRetrospective StudiesSARS-CoV-2

Identifiers

PMID36906638
PMCPMC10007654
OpenAlexW4323971835

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.