Evidence map›Paper›PMID 36906280›Full record

ArticleLetters in applied microbiology2023

Efficacy of detergent-based cleaning and wiping against SARS-CoV-2 on high-touch surfaces.

S W Nelson, R L Hardison, R Limmer, J Marx, B M Taylor, R R James, M J Stewart, S D Lee, M W Calfee, S P Ryan and 1 more

Abstract read
In one paragraph

Article in Letters in applied microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S W NelsonBioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA.
R L HardisonBioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA.
R LimmerBattelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA.
J MarxBattelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA.
B M TaylorBattelle Eastern Science and Technology Center, Aberdeen, MD 21001, USA.
R R JamesBioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA.
M J StewartU.S. EPA, Office of Research and Development, Durham, NC 27711, USA.
S D LeeU.S. EPA, Office of Research and Development, Durham, NC 27711, USA.
M W CalfeeU.S. EPA, Office of Research and Development, Durham, NC 27711, USA.
S P RyanU.S. EPA, Office of Research and Development, Durham, NC 27711, USA.
M W HowardBioscience Center, Battelle Memorial Institute, Columbus, OH 43201, USA.

Funding

Battelle Memorial Institute 68HERC20F0241Intramural EPA EPA999999
6 · The paper itself

Abstract

Efficacy of cleaning methods against SARS-CoV-2 suspended in either 5% soil load (SARS-soil) or simulated saliva (SARS-SS) was evaluated immediately (hydrated virus, T0) or 2 hours post-contamination (dried virus, T2). Hard water dampened wiping (DW) of surfaces, resulted in 1.77-3.91 log reduction (T0) or 0.93-2.41 log reduction (T2). Incorporating surface pre-wetting by spraying with a detergent solution (D + DW) or hard water (W + DW) just prior to dampened wiping did not unilaterally increase efficacy against infectious SARS-CoV-2, however, the effect was nuanced with respect to surface, viral matrix, and time. Cleaning efficacy on porous surfaces (seat fabric, SF) was low. W + DW on stainless steel (SS) was as effective as D + DW for all conditions except SARS-soil at T2 on SS. DW was the only method that consistently resulted in > 3-log reduction of hydrated (T0) SARS-CoV-2 on SS and ABS plastic. These results suggest that wiping with a hard water dampened wipe can reduce infectious virus on hard non-porous surfaces. Pre-wetting surfaces with surfactants did not significantly increase efficacy for the conditions tested. Surface material, presence or absence of pre-wetting, and time post-contamination affect efficacy of cleaning methods.

Indexed as

COVID-19VirusesDetergentsDisinfectionHumansSARS-CoV-2TouchWaterDetergentsWatercleaningcoronavirusdisinfectionhigh-touch surfacesSARS-CoV-2surfactantvirucidevirus

Identifiers

PMID36906280
PMCPMC11417498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.