Evidence map›Paper›PMID 36906180›Full record

ArticleThe Journal of hospital infection2023

Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes.

S Cotton, M P McHugh, R Dewar, J G Haas, K Templeton, COVID-19 Genomics UK (COG-UK) Consortium

Abstract read
In one paragraph

Article in The Journal of hospital infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

S CottonSpecialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, UK; Infection Medicine, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK. Electronic address: Seb.cotton@nhslothian.scot.nhs.uk.
M P McHughSpecialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, UK; School of Medicine, University of St Andrews, St Andrews, UK.
R DewarSpecialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, UK.
J G HaasSpecialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, UK; Infection Medicine, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.
K TempletonSpecialist Virology Centre, Royal Infirmary of Edinburgh, Edinburgh, UK; Infection Medicine, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.
COVID-19 Genomics UK (COG-UK) ConsortiumDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

Funding

Medical Research Council MR/P011349/1Medical Research Council MR/S035362/1
6 · The paper itself

Abstract

backgroundThe first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes.

aimTo investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave.

methodsA clinical review was performed for all patients discharges from hospitals to care homes from 1

findingsIn total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home.

conclusionThe majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine.

Indexed as

COVID-19SARS-CoV-2HospitalizationHospitalsHumansPatient DischargeCare homesHospital dischargeIntroductionSARS-CoV-2

Identifiers

PMID36906180
PMCPMC9997060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.