Evidence map›Paper›PMID 36905513›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors.

Pierre Bourdely, Roberto Savoldelli, Mathias Vetillard, Giorgio Anselmi, Julie Helft, Pierre Guermonprez

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Pierre Bourdely *Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris Cité, Paris, France. pierre.bourdely@inserm.fr.
Roberto Savoldelli *King's College London, Centre for Inflammation Biology and Cancer Immunology, London, UK.
Mathias Vetillard *Université de Paris, INSERM U1149, CNRS erl8252, Centre for Inflammation Research, Université de Paris Cité, Paris, France.
Giorgio AnselmiKing's College London, Centre for Inflammation Biology and Cancer Immunology, London, UK.
Julie HelftInstitut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris Cité, Paris, France.
Pierre GuermonprezUniversité de Paris, INSERM U1149, CNRS erl8252, Centre for Inflammation Research, Université de Paris Cité, Paris, France. pierre.guermonprez@cnrs.fr.
Centre National de la Recherche Scientifique · FRInserm · FRJohn Radcliffe Hospital · GBUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are professional antigen-presenting cells controlling the activation of T cells and thus regulating adaptive immune response against pathogens or tumors. Modeling human DC differentiation and function is crucial for our understanding of immune response and the development of new therapies. Considering DC rarity in human blood, in vitro systems allowing their faithful generation are needed. This chapter will describe a DC differentiation method based on the co-culture of CD34

Indexed as

Dendritic CellsFetal BloodAntigens, CD34Cell Adhesion MoleculesCell DifferentiationCells, CulturedHumansAntigens, CD34Cell Adhesion MoleculesCD34Conventional dendritic cellsCord bloodDendritic cellsHematopoietic stem cellsIn vitro differentiationMesenchymal stromal cellsPlasmacytoid dendritic cell

Identifiers

PMID36905513
OpenAlexW4323921222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.