Evidence map›Paper›PMID 36905496›Full record

ArticleAIDS and behavior2023

Addressing the Know-Do Gap in Adolescent HIV: Framing and Measuring Implementation Determinants, Outcomes, and Strategies in the AHISA Network.

Kristin Beima-Sofie, Irene Njuguna, Tessa Concepcion, Stephanie M DeLong, Geri Donenberg, Brian C Zanoni, Dorothy Dow, Paula Braitstein, Anjuli Wagner

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In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristin Beima-Sofie *Department of Global Health, University of Washington, Seattle, WA, USA. beimak@uw.edu.ORCID http://orcid.org/0000-0002-3408-7410
Irene Njuguna *Department of Global Health, University of Washington, Seattle, WA, USA.
Tessa ConcepcionDepartment of Global Health, University of Washington, Seattle, WA, USA.
Stephanie M DeLongDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Geri DonenbergCenter for Dissemination and Implementation Science (CDIS), Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Brian C ZanoniDepartments of Medicine and Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Dorothy DowDepartment of Pediatrics, Infectious Diseases, Duke University School of Medicine, Durham, NC, USA.
Paula BraitsteinDivision of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Anjuli WagnerDepartment of Global Health, University of Washington, Seattle, WA, USA.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI CHWASTIAK, LYDIA ANN · 2021 to 2024
$5.8M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
Testing implementation strategies to improve delivery of PrEP for pregnant and postpartum women in KenyaK01MH121124 · NIMH · UNIVERSITY OF WASHINGTON · PI WAGNER, ANJULI DAWN · 2019 to 2023
$835k
Understanding the role of schools in supporting HIV treatment outcomes among HIV infected adolescentsK43TW011422 · FIC · KENYATTA NATIONAL HOSPITAL · PI NJUGUNA, IRENE NYAMBURA · 2020 to 2024
$603k
FIC NIH HHS K43 TW011422FIC NIH HHS K43TW011422-01A1NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI102623NIMH NIH HHS K01 MH121124NIMH NIH HHS K01MH121124NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

Implementation science (IS) uses systematic methods to close gaps between research and practice by identifying and addressing barriers to implementation of evidence-based interventions (EBIs). To reach UNAIDS HIV targets, IS can support programs to reach vulnerable populations and achieve sustainability. We studied the application of IS methods in 36 study protocols that were part of the Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA). Protocols focused on youth, caregivers, or healthcare workers in high HIV-burden African countries and evaluated medication, clinical and behavioral/social EBIs. All studies measured clinical outcomes and implementation science outcomes; most focused on early implementation outcomes of acceptability (81%), reach (47%), and feasibility (44%). Only 53% used an implementation science framework/theory. Most studies (72%) evaluated implementation strategies. Some developed and tested strategies, while others adapted an EBI/strategy. Harmonizing IS approaches allows cross study learning and optimization of delivery of EBIs and could support attainment of HIV goals.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsAdolescentAfricaHealth PersonnelHumansAdolescent/youth HIVImplementation scienceKnow-do gap

Identifiers

PMID36905496
PMCPMC10007651

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read2
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.