SynthesisEuropean journal of pediatrics2023
Systematic review of long term follow-up and transitional care in adolescents and adults with esophageal atresia - why is transitional care mandatory?
Synthesis in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Management of gastroesophageal reflux disease following esophageal atresia surgery: a systematic review.Pediatric surgery international · 2025Pooled it
- The long-term follow-up outcomes and transition rates across seven representative pediatric congenital surgical conditions: disease severity drives follow-up retention.Pediatric surgery international · 2026Article
- Respiratory Morbidity After Repair of Type C Esophageal Atresia with Tracheoesophageal Fistula: A Pediatric Case Series.Journal of clinical medicine · 2026Article
- Adult outcomes following neonatal oesophageal atresia: more reasons to be concerned?Pediatric research · 2026Article
- Transitioning Adolescents and Young Adults With Neurogastroenterology and Motility Disorders to Adult Care. Current Practices and Challenges in North America.Neurogastroenterology and motility · 2026Article
- Adults following open esophageal atresia repair: evaluating long-term musculoskeletal and pulmonary outcomes using insights from real-time MRI.Pediatric research · 2026Article
- Handing off hope: transition of care in pediatric surgery.Surgical endoscopy · 2026Review
- Retrospective case-control study of nutritional and respiratory status in children with type III esophageal atresia.Journal of pediatric gastroenterology and nutrition · 2026Observational
- Esophageal Atresia: From worry to wisdom-Global pediatrics · 2025Article
- Questionnaire survey on the long-term quality of life of patients with congenital esophageal atresia in Japan.Surgery today · 2025Article
- Aortopexy for Tracheomalacia in Children: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Follow-up and transition practices in esophageal atresia: a review of European Reference Network on rare Inherited and Congenital Anomalies (ERNICA) centres and affiliates.Pediatric surgery international · 2024Article
- Navigating the transition: a multidisciplinary approach to inflammatory bowel disease in children.Pediatric surgery international · 2024Observational
- Major surgical conditions of childhood and their lifelong implications: comprehensive review.BJS open · 2024Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeto review recent literature concerning long-term health issues and transitional care in esophageal atresia (EA) patients. PubMed, Scopus, Embase and Web of Science databases were screened for studies regarding EA patients aged more than or equal to 11 years, published between August 2014 and June 2022. Sixteen studies involving 830 patients were analyzed. Mean age was 27.4 years (range 11-63). EA subtype distribution was: type C (48.8%), A (9.5%), D (1.9%), E (0.5%) and B (0.2%). 55% underwent primary repair, 34.3% delayed repair, 10.5% esophageal substitution. Mean follow-up was 27.2 years (range 11-63). Long-term sequelae were: gastro-esophageal reflux (41.4%), dysphagia (27.6%), esophagitis (12.4%), Barrett esophagus (8.1%), anastomotic stricture (4.8%); persistent cough (8.7%), recurrent infections (4.3%) and chronic respiratory diseases (5.5%). Musculo-skeletal deformities were present in 36 out of 74 reported cases. Reduced weight and height were detected in 13.3% and 6% cases, respectively. Impaired quality of life was reported in 9% of patients; 9.6% had diagnosis or raised risk of mental disorders. 10.3% of adult patients had no care provider. Meta-analysis was conducted on 816 patients. Estimated prevalences are: GERD 42.4%, dysphagia 57.8%, Barrett esophagus 12.4%, respiratory diseases 33.3%, neurological sequelae 11.7%, underweight 19.6%. Heterogeneity was substantial (> 50%). Conclusion: EA patients must continue follow-up beyond childhood, with a defined transitional-care path by a highly specialized multidisciplinary team due to the multiple long-term sequelae. WHAT IS KNOWN: • Survival rates of esophageal atresia patients is now more than 90% thanks to the improvements in surgical techniques and intensive care, therefore patients' needs throughout adolescence and adulthood must be taken into account. WHAT IS NEW: • This review, by summarizing recent literature concerning long term sequelae of esophageal atresia, may contribute to raise awareness on the importance of defining standardized protocols of transitional and adulthood care for esophageal atresia patients.
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