Evidence map›Paper›PMID 36905151›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis.

Arash Heidari, Rupam Sharma, Qusai Shakir, Madiha Shah, Josh Clement, Monica A Donnelley, Trina Reynolds, Kate Trigg, Jeff Jolliff, Rasha Kuran and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Fosmanogepix Treatment for Coccidioidomycosis Under an Expanded Access Program.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Killing ofMicrobiology (Reading, England) · 2026
    Article
  3. Article
  4. Insights into current coccidioidomycosis therapeutic pathways.Antimicrobial agents and chemotherapy · 2025
    Article
  5. Drug Discovery and Repurposing forJournal of fungi (Basel, Switzerland) · 2025
    Review
  6. Overview of the Current Challenges in Pulmonary Coccidioidomycosis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Arash HeidariDepartment of Medicine, Division of Infectious Diseases, Kern Medical Center-University of California-Los Angeles, Bakersfield, California, USA.
Rupam SharmaValley Fever Institute, Bakersfield, California, USA.
Qusai ShakirValley Fever Institute, Bakersfield, California, USA.
Madiha ShahDepartment of Pharmacy, University of California-Davis Medical Center, Sacramento, California, USA.
Josh ClementDepartment of Pharmacy, University of California-Davis Medical Center, Sacramento, California, USA.
Monica A DonnelleyDepartment of Pharmacy, University of California-Davis Medical Center, Sacramento, California, USA.
Trina ReynoldsDepartment of Internal Medicine, Division of Infectious Diseases, University of California-Davis Medical Center, Sacramento, California, USA.
Kate TriggDepartment of Internal Medicine, Division of Infectious Diseases, University of California-Davis Medical Center, Sacramento, California, USA.
Jeff JolliffDepartment of Medicine, Division of Infectious Diseases, Kern Medical Center-University of California-Los Angeles, Bakersfield, California, USA.
Rasha KuranDepartment of Medicine, Division of Infectious Diseases, Kern Medical Center-University of California-Los Angeles, Bakersfield, California, USA.
Royce JohnsonDepartment of Medicine, Division of Infectious Diseases, Kern Medical Center-University of California-Los Angeles, Bakersfield, California, USA.
George R ThompsonDepartment of Internal Medicine, Division of Infectious Diseases, University of California-Davis Medical Center, Sacramento, California, USA.
University of California Davis Medical Center · USUniversity of California, Los Angeles · US

Funding

Virulence gene discovery in CoccidioidesU19AI166798 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Anita Sil · 2022 to 2026
$10.5M
NIAID NIH HHS U19 AI166798NIH HHS 5U19AI166798)
6 · The paper itself

Abstract

Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis.

Indexed as

CoccidioidomycosisAntifungal AgentsCoccidioidesHumansNitrilesPyridinesTriazolesAntifungal AgentsisavuconazoleNitrilesPyridinesTriazolesantifungalCoccidioidesisavuconazoniumtreatmentValley fever

Identifiers

PMID36905151
PMCPMC10893960
OpenAlexW4323921210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.