ArticlePolymers2023
Biodegradable Polylactic Acid-Polyhydroxyalkanoate-Based Nanocomposites with Bio-Hydroxyapatite: Preparation and Characterization.
Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sustainable clear aligner practice in esthetic and prosthetic dentistry: a scoping review for practical implementation.Frontiers in oral health · 2026Pooled it
- Electrospun Fibrous Architectures for Localized Delivery of Photosensitizers in Cancer Therapy.Molecules (Basel, Switzerland) · 2026Article
- Recent advances in biomaterials for bone regeneration: Bridging innovation and clinical translation.Materials today. Bio · 2026Review
- From Waste to Treasure: Therapeutic Horizons of Polyhydroxyalkanoates in Modern Medicine.Pharmaceutics · 2026Review
- EngineeringBiodesign research · 2025Article
- Biodegradation of Poly(ε-caprolactone): Microorganisms, Enzymes, and Mechanisms.International journal of molecular sciences · 2025Review
- A review on bio-based polymer polylactic acid potential on sustainable food packaging.Food science and biotechnology · 2024Review
- Article
- Biodegradable Polylactic Acid and Its Composites: Characteristics, Processing, and Sustainable Applications in Sports.Polymers · 2023Review
- Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing.Pharmaceutics · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Biodegradable polymers play a significant role in medical applications, especially internal devices because they can be broken down and absorbed into the body without producing harmful degradation products. In this study, biodegradable polylactic acid (PLA)-polyhydroxyalkanoate (PHA)-based nanocomposites with various PHA and nano-hydroxyapatite (nHAp) contents were prepared using solution casting method. Mechanical properties, microstructure, thermal stability, thermal properties, and in vitro degradation of the PLA-PHA-based composites were investigated. PLA-20PHA/5nHAp was shown to give the desired properties so it was selected to investigate electrospinnability at different applied high voltages. PLA-20PHA/5nHAp composite shows the highest improvement of tensile strength at 36.6 ± 0.7 MPa, while PLA-20PHA/10nHAp composite shows the highest thermal stability and in vitro degradation at 7.55% of weight loss after 56 days of immersion in PBS solution. The addition of PHA in PLA-PHA-based nanocomposites improved elongation at break, compared to the composite without PHA. PLA-20PHA/5nHAp solution was successfully fabricated into fibers by electrospinning. All obtained fibers showed smooth and continuous fibers without beads with diameters of 3.7 ± 0.9, 3.5 ± 1.2, and 2.1 ± 0.7 µm at applied high voltages of 15, 20, and 25 kV, respectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.