Evidence map›Paper›PMID 36904331›Full record

ArticlePolymers2023

Turmeric Herb Extract-Incorporated Biopolymer Dressings with Beneficial Antibacterial, Antioxidant and Anti-Inflammatory Properties for Wound Healing.

Piyachat Chuysinuan, Chalinan Pengsuk, Kriengsak Lirdprapamongkol, Thanyaluck Thanyacharoen, Supanna Techasakul, Jisnuson Svasti, Patcharakamon Nooeaid

Full text read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.International journal of molecular sciences · 2024
    Review
  12. Turmeric and Curcumin-Health-Promoting Properties in Humans versus Dogs.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Piyachat ChuysinuanLaboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Chalinan PengsukDivision of Biotechnology Technology and Agricultural Products, Faculty of Agricultural Product Innovation and Technology, Srinakharinwirot University, Ongkarak, Nakhon Nayok 26120, Thailand.
Kriengsak LirdprapamongkolLaboratory of Biochemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.ORCID 0000-0001-5858-5433
Thanyaluck ThanyacharoenLaboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Supanna TechasakulLaboratory of Organic Synthesis, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Jisnuson SvastiLaboratory of Biochemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.ORCID 0000-0002-2217-4517
Patcharakamon NooeaidDivision of Polymer Materials Technology, Faculty of Agricultural Product Innovation and Technology, Srinakharinwirot University, Ongkarak, Nakhon Nayok 26120, Thailand.ORCID 0000-0001-8151-8562

Funding

Srinakharinwirot University 603/2563Thailand research and innovation, Chulabhorn research institute 2536703/42324Thailand Research and Innovation, Chulabhorn Research Institute 2536708/41864
6 · The paper itself

Abstract

Bacterial infection and inflammation caused by excess oxidative stress are serious challenges in chronic wound healing. The aim of this work is to investigate a wound dressing based on natural- and biowaste-derived biopolymers loaded with an herb extract that demonstrates antibacterial, antioxidant, and anti-inflammatory activities without using additional synthetic drugs. Turmeric extract-loaded carboxymethyl cellulose/silk sericin dressings were produced by esterification crosslinking with citric acid followed by freeze-drying to achieve an interconnected porous structure, sufficient mechanical properties, and hydrogel formation in situ in contact with an aqueous solution. The dressings exhibited inhibitory effects on the growth of bacterial strains that were related to the controlled release of the turmeric extract. The dressings provided antioxidant activity as a result of the radical scavenging effect on DPPH, ABTS, and FRAP radicals. To confirm their anti-inflammatory effects, the inhibition of nitric oxide production in activated RAW 264.7 macrophages was investigated. The findings suggested that the dressings could be a potential candidate for wound healing.

Indexed as

antibacterial propertyanti-inflammatory propertyantioxidant activitybiopolymersturmeric extractwound dressing

Identifiers

PMID36904331
PMCPMC10007553

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read119
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.