Evidence map›Paper›PMID 36904298›Full record

ArticleNutrients2023

Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.

Xinsheng Zhang, Peng Zhang, Yinghua Liu, Zhao Liu, Qing Xu, Yong Zhang, Lu Liu, Xueyan Yang, Liya Li, Changyong Xue

Full text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Modulatory effects of exogenous estradiol during endotoxemia.The international journal of biochemistry & cell biology · 2026
    Article
  4. Review
  5. Article
  6. Relationship between Indel Variants within theAnimals : an open access journal from MDPI · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinsheng ZhangDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Peng ZhangGuizhou Crops of Chinese People's Armed Police Force, Guiyang 550001, China.
Yinghua LiuDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Zhao LiuDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Qing XuDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Yong ZhangDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Lu LiuDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Xueyan YangDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Liya LiDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Changyong XueDepartment of Nutrition, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.

Funding

The National Natural Science Fund of China 81703204
6 · The paper itself

Abstract

Our previous studies have found that caprylic acid (C8:0) can improve blood lipids and reduce inflammation levels and may be related to the upregulation of the p-JAK2/p-STAT3 pathway by ABCA1. This study aims to investigate the effects of C8:0 and eicosapentaenoic acid (EPA) on lipids, inflammatory levels, and the JAK2/STAT3 pathway in ABCA1-deficient mice (ABCA1

Indexed as

Eicosapentaenoic AcidInterleukin-10AnimalsATP Binding Cassette Transporter 1CaprylatesInflammationLipopolysaccharidesMiceRAW 264.7 CellsRNA, MessengerToll-Like Receptor 4Tumor Necrosis Factor-alphaAbca1 protein, mouseATP Binding Cassette Transporter 1CaprylatesEicosapentaenoic AcidInterleukin-10Lipopolysaccharidesoctanoic acidRNA, MessengerToll-Like Receptor 4Tumor Necrosis Factor-alphaABCA1caprylic acidEPAinflammatory cytokineJAK2STAT3

Identifiers

PMID36904298
PMCPMC10005197

What OpenQuestion holds

Textfull text, public
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measurements read43
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.