Evidence map›Paper›PMID 36904208›Full record

ArticleNutrients2023

The Effect of Omega-9 on Bone Viscoelasticity and Strength in an Ovariectomized Diet-Fed Murine Model.

Mahmoud Omer, Christopher Ngo, Hessein Ali, Nina Orlovskaya, Vee San Cheong, Amelia Ballesteros, Michael Tyrel Garner, Austin Wynn, Kari Martyniak, Fei Wei and 11 more

Full text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Effects ofInternational journal of molecular sciences · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Mahmoud OmerBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.
Christopher NgoBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.
Hessein AliDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.
Nina OrlovskayaDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.
Vee San CheongInsigneo Institute for In Silico Medicine, University of Sheffield, Sheffield S1 3JD, UK.
Amelia BallesterosBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.
Michael Tyrel GarnerCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Austin WynnCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Kari MartyniakBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.
Fei WeiBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.ORCID 0000-0001-7577-6143
Boyce E CollinsEngineering Research Center for Revolutionizing Biomaterials, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0003-3238-0987
Sergey N YarmolenkoEngineering Research Center for Revolutionizing Biomaterials, North Carolina A&T State University, Greensboro, NC 27411, USA.
Jackson AsiaticoDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.
Michael KinzelDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-8928-2814
Ranajay GhoshDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL 32816, USA.
Teerin MeckmongkolBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.
Ashley CalderCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Naima DahirCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Timothy A GilbertsonCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.ORCID 0000-0003-2569-3096
Jagannathan SankarEngineering Research Center for Revolutionizing Biomaterials, North Carolina A&T State University, Greensboro, NC 27411, USA.
Melanie CoathupBiionix Cluster, University of Central Florida, Orlando, FL 32827, USA.ORCID 0000-0002-4543-4756

Funding

FATTY ACID RECEPTORS IN GUSTATIONR01DC013318 · NIDCD · UTAH STATE UNIVERSITY · PI GILBERTSON, TIMOTHY A. · 2014 to 2018
$1.5M
NIDCD NIH HHS R01 DC013318
6 · The paper itself

Abstract

Few studies have investigated the effect of a monosaturated diet high in ω-9 on osteoporosis. We hypothesized that omega-9 (ω-9) protects ovariectomized (OVX) mice from a decline in bone microarchitecture, tissue loss, and mechanical strength, thereby serving as a modifiable dietary intervention against osteoporotic deterioration. Female C57BL/6J mice were assigned to sham-ovariectomy, ovariectomy, or ovariectomy + estradiol treatment prior to switching their feed to a diet high in ω-9 for 12 weeks. Tibiae were evaluated using DMA, 3-point-bending, histomorphometry, and microCT. A significant decrease in lean mass (

Indexed as

Fractures, BoneOsteoporosisAnimalsBone DensityCross-Sectional StudiesDietDisease Models, AnimalFemaleHumansMiceMice, Inbred C57BLOvariectomyViscositydietfractureomega-9osteoporosisviscoelasticity

Identifiers

PMID36904208
PMCPMC10005705

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.