ArticleNutrients2023
A Mendelian Randomization Analysis Investigates Causal Associations between Inflammatory Bowel Diseases and Variable Risk Factors.
Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Type 2 diabetes and inflammatory bowel disease: a bidirectional two-sample Mendelian randomization study.Scientific reports · 2024Pooled it
- Article
- Causal Associations Between Sleep Traits and Polycystic Ovary Syndrome: A Univariable, Bidirectional, and Multivariable Mendelian Randomization Study.The journal of obstetrics and gynaecology research · 2026Article
- Causality Between Irritable Bowel Syndrome and Suicide Attempt: A Mendelian Randomization Study.Brain and behavior · 2025Article
- Dietary content and eating behavior in ulcerative colitis: a narrative review and future perspective.Nutrition journal · 2025Review
- Mendelian randomization analysis reveals causal relationship between tonsillectomy and irritable bowel syndrome.Frontiers in surgery · 2025Article
- A Prospective Study on the Association of Mediterranean Diet Adherence and Physical Activity with Inflammatory Bowel Disease in Children.Journal of inflammation research · 2025Article
- The associations between modifiable risk factors and constipation: a comprehensive mendelian randomization study.BMC gastroenterology · 2024Article
- Serum amyloid A for predicting prognosis in patients with newly diagnosed Crohn's disease.BMJ open gastroenterology · 2024Article
- The Role of Environmental and Nutritional Factors in the Development of Inflammatory Bowel Diseases: A Case-Control Study.Nutrients · 2024Article
- Article
- Environmental and Microbial Factors in Inflammatory Bowel Disease Model Establishment: A Review Partly through Mendelian Randomization.Gut and liver · 2024Review
- Mendelian randomisation analysis for intestinal disease: achievement and future.eGastroenterology · 2024Review
- Article
- NLRP3 Inflammasome and Gut Dysbiosis Linking Diabetes Mellitus and Inflammatory Bowel Disease.Archives of internal medicine research · 2024Article
- Genetic Association between Lipid-Regulating Drug Targets and Diabetic Retinopathy: A Drug Target Mendelian Randomization Study.Journal of lipids · 2024Article
- Causality between sleep traits and the risk of frailty: a Mendelian randomization study.Frontiers in public health · 2024Article
- Exploring the causality of appendectomy and ischaemic heart disease: a Mendelian randomization study and meta-analysis.Frontiers in cardiovascular medicine · 2024Article
- Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.Frontiers in genetics · 2024Article
- Causal relationship between green tea intake and gastrointestinal disorders: a two-sample Mendelian randomization study.Frontiers in nutrition · 2024Article
Corrections and comments
- Retraction · 2024-06-06Concerns/Issues about Authorship/Affiliation · Investigation by Journal/Publisher · Unreliable Results and/or Conclusions ·
- Retracted
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The question of whether variable risk factors and various nutrients are causally related to inflammatory bowel diseases (IBDs) has remained unanswered so far. Thus, this study investigated whether genetically predicted risk factors and nutrients play a function in the occurrence of inflammatory bowel diseases, including ulcerative colitis (UC), non-infective colitis (NIC), and Crohn's disease (CD), using Mendelian randomization (MR) analysis. Utilizing the data of genome-wide association studies (GWASs) with 37 exposure factors, we ran Mendelian randomization analyses based on up to 458,109 participants. Univariable and multivariable MR analyses were conducted to determine causal risk factors for IBD diseases. Genetic predisposition to smoking and appendectomy as well as vegetable and fruit intake, breastfeeding,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.