Evidence map›Paper›PMID 36904195›Full record

ArticleNutrients2023

Metabolic Profile of Patients with Long COVID: A Cross-Sectional Study.

Daniel Carvalho de Menezes, Patrícia Danielle Lima de Lima, Igor Costa de Lima, Juliana Hiromi Emin Uesugi, Pedro Fernando da Costa Vasconcelos, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão

Full text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Treatment with Sulodexide Downregulates Biomarkers for Endothelial Dysfunction in Convalescent COVID-19 Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
  3. Review
  4. Cellular Metabolic Signatures of Long COVID-19.Infectious disease reports · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Cardiovascular Symposium on Perspectives in Long COVID.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel Carvalho de MenezesCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.
Patrícia Danielle Lima de LimaCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.
Igor Costa de LimaCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.
Juliana Hiromi Emin UesugiCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.ORCID 0000-0002-1158-166X
Pedro Fernando da Costa VasconcelosCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.
Juarez Antônio Simões QuaresmaCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.ORCID 0000-0002-6267-9966
Luiz Fábio Magno FalcãoCenter for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.ORCID 0000-0001-8391-2694

Funding

AMAZON FOUNDATION FOR RESEARCH SUPPORT #006/2020CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - Brazil INCT: 406360/2022-7COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - Brazil Notice n° 13/2020SECRETARY OF SCIENCE, TECHNOLOGY, AND HIGHER, PROFESSIONAL AND TECH-NOLOGICAL EDUCATION #09/2021
6 · The paper itself

Abstract

A significant proportion of patients experience a wide range of symptoms following acute coronavirus disease 2019 (COVID-19). Laboratory analyses of long COVID have demonstrated imbalances in metabolic parameters, suggesting that it is one of the many outcomes induced by long COVID. Therefore, this study aimed to illustrate the clinical and laboratory markers related to the course of the disease in patients with long COVID. Participants were selected using a clinical care programme for long COVID in the Amazon region. Clinical and sociodemographic data and glycaemic, lipid, and inflammatory screening markers were collected, and cross-sectionally analysed between the long COVID-19 outcome groups. Of the 215 participants, most were female and not elderly, and 78 were hospitalised during the acute COVID-19 phase. The main long COVID symptoms reported were fatigue, dyspnoea, and muscle weakness. Our main findings show that abnormal metabolic profiles (such as high body mass index measurement and high triglyceride, glycated haemoglobin A1c, and ferritin levels) are more prevalent in worse long COVID presentations (such as previous hospitalisation and more long-term symptoms). This prevalence may suggest a propensity for patients with long COVID to present abnormalities in the markers involved in cardiometabolic health.

Indexed as

COVID-19Cross-Sectional StudiesFemaleHumansMaleMetabolomePost-Acute COVID-19 SyndromeSARS-CoV-2cardiometabolic risk factorslaboratory markerslong COVID

Identifiers

PMID36904195
PMCPMC10005061

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.