Evidence map›Paper›PMID 36904178›Full record

ArticleNutrients2023

Fecal Calprotectin Elevations Associated with Food Intolerance/Malabsorption Are Significantly Reduced with Targeted Diets.

Wolfgang J Schnedl, Simon Michaelis, Dietmar Enko, Harald Mangge

Registry-linked trialFull text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07424898 (Observational Cross-Sectional Study of Intestinal Permeability in Adults With Lactose Intolerance), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07424898 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Observational Cross-Sectional Study of Intestinal Permeability in Adults With Lactose Intolerance

Typeobservational_patient_registrySponsorBezmialem Vakif UniversityRan2026 to 2027Enrolled200ConditionsLactose Intolerance, Adult Type, Intestinal Permability, IBS (Irritable Bowel Syndrome)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wolfgang J SchnedlDepartment of Internal Medicine, Auenbruggerplatz 15, A-8036 Graz, Austria.ORCID 0000-0002-5212-5230
Simon MichaelisInstitute of Clinical Chemistry and Laboratory Medicine, Hospital Hochsteiermark, Vordernberger Straße 42, A-8700 Leoben, Austria.
Dietmar EnkoInstitute of Clinical Chemistry and Laboratory Medicine, Hospital Hochsteiermark, Vordernberger Straße 42, A-8700 Leoben, Austria.ORCID 0000-0002-1173-0928
Harald ManggeClinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz, Auenbruggerplatz 30, A-8036 Graz, Austria.ORCID 0000-0002-5182-4558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) involves two clinically defined entities, namely Crohn's disease and ulcerative colitis. Fecal calprotectin (FCAL) is used as a marker to distinguish between organic IBD and functional bowel disease in disorders of the irritable bowel syndrome (IBS) spectrum. Food components may affect digestion and cause functional abdominal disorders of the IBS spectrum. In this retrospective study, we report on FCAL testing to search for IBD in 228 patients with disorders of the IBS spectrum caused by food intolerances/malabsorption. Included were patients with fructose malabsorption (FM), histamine intolerance (HIT), lactose intolerance (LIT), and

Indexed as

Fructose IntoleranceInflammatory Bowel DiseasesIrritable Bowel SyndromeLactose IntoleranceMalabsorption SyndromesDietFecesFood IntoleranceFructoseHistamineHumansLeukocyte L1 Antigen ComplexRetrospective StudiesFructoseHistamineLeukocyte L1 Antigen Complexfecal calprotectinfructose malabsorptionhistamine intoleranceinflammatory bowel diseaseirritable bowel syndromelactose intolerance

Identifiers

PMID36904178
PMCPMC10005609

What OpenQuestion holds

Textfull text, public
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.