ArticleNutrients2023
Association between Systemic Immunity-Inflammation Index and Hyperlipidemia: A Population-Based Study from the NHANES (2015-2020).
Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 1 of them a synthesis that pooled it.
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Who cites it
192 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of systemic immune-inflammation index with type 2 diabetes mellitus and its prognostic significance: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Randomized clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits.Frontiers in immunology · 2025Trial
- Association of CBC‑derived inflammation indices with prevalent CKD: a cross‑sectional analysis of a Chinese data set and NHANES.Annals of medicine · 2026Article
- The U-shaped correlation between the systemic immune-inflammation index and all-cause and cardiovascular mortality in hyperlipidemic patients: findings from NHANES 1999-2018.Annals of medicine · 2026Article
- U-Shaped Association Between Serum Vitamin B12 and All-Cause Mortality in Adults With Obesity in the United States: A Prospective Cohort Study.Current therapeutic research, clinical and experimental · 2026Article
- Article
- Association of Serum Parathyroid Hormone Levels with All-Cause and Cause-Specific Mortality Among U.S. Adults, with a Focus on the Parathyroid Hormone Levels Within the Normal Range: a Population-Based Cohort Study from NHANES 2003-2006.Calcified tissue international · 2026Article
- Associations between 12 insulin resistance surrogates with metabolic dysfunction-associated steatotic liver disease risk and all-cause mortality: data from the NHANES III (1988-1994).European journal of gastroenterology & hepatology · 2026Article
- Observational
- Body fat percentage and hypertension risk: A population-based observational and Mendelian randomization study.Medicine · 2026Observational
- Article
- Association between the systemic immune-inflammation index and risk of osteoarthritis: a cross-sectional NHANES 2013-2018 study.Clinical rheumatology · 2026Article
- Effect of epidural analgesia on the neutrophil-to-lymphocyte ratio after thoracic surgery: a large-scale retrospective cohort study.Journal of thoracic disease · 2026Article
- Predictive role of systemic immune-inflammation index (SII) in tuberculosis infection morbidity and ICU tuberculosis patient mortality: an observational study.Journal of thoracic disease · 2026Article
- Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.NPJ science of food · 2026Article
- Association between systemic immune-inflammation index and urinary incontinence: Evidence from the National Health and Nutrition Examination Survey.The Journal of international medical research · 2026Article
- Association between the newly proposed triglyceride glucose-a body shape index (TyG-ABSI) and atherosclerotic cardiovascular disease in the general population: modest diagnostic improvement compared with traditional TyG-related parameters.Cardiovascular diabetology · 2026Article
- Association Between Neutrophil-Percentage-To-Albumin Ratio Level and Heart Failure in Hypertensive Population.International journal of hypertension · 2026Article
- Combined discriminative value of SII and sdLDL-C for 1-year major adverse cardiovascular events in patients with unstable angina pectoris.Frontiers in cardiovascular medicine · 2026Article
- Article
132 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
Abstract
The systemic immunity-inflammation index (SII) is a novel inflammatory marker, and aberrant blood lipid levels are linked to inflammation. This study aimed to look at the probable link between SII and hyperlipidemia. The current cross-sectional investigation was carried out among people with complete SII and hyperlipidemia data from the 2015-2020 National Health and Nutrition Examination Survey (NHANES). SII was computed by dividing the platelet count × the neutrophil count/the lymphocyte count. The National Cholesterol Education Program standards were used to define hyperlipidemia. The nonlinear association between SII and hyperlipidemia was described using fitted smoothing curves and threshold effect analyses. A total of 6117 US adults were included in our study. A substantial positive correlation between SII and hyperlipidemia was found [1.03 (1.01, 1.05)] in a multivariate linear regression analysis. Age, sex, body mass index, smoking status, hypertension, and diabetes were not significantly correlated with this positive connection, according to subgroup analysis and interaction testing (
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