Evidence map›Paper›PMID 36904164›Full record

ReviewNutrients2023

Inflammation and Nutrition: Friend or Foe?

Franziska Stumpf, Bettina Keller, Carla Gressies, Philipp Schuetz

Open access · goldFull text readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 6 pooled it
29.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 6 syntheses or guidelines pooled it, 169 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Enteral nutrition support in patients with cancer: association of short-term prognosis and medical costs with inflammation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  8. Trial
  9. Article
  10. Article
  11. Review
  12. Continuously elevated plasma ketone bodies are linked to adverse outcomes in patients with heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Franziska StumpfMedical University Department of Medicine, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Bettina KellerMedical University Department of Medicine, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0003-2173-7848
Carla GressiesMedical University Department of Medicine, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0003-1720-6462
Philipp SchuetzMedical University Department of Medicine, Division of General Internal and Emergency Medicine, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0001-6400-4949
University of Basel · CHKantonsspital Aarau · CHUniversity of Hohenheim · DE

Funding

Kantonsspital Aarau 1410.000.044Kantonsspital Aarau 1410.000.058Swiss National Science Foundation PP00P3_150531
6 · The paper itself

Abstract

The importance of the interplay between inflammation and nutrition has generated much interest in recent times. Inflammation has been identified as a key driver for disease-related malnutrition, leading to anorexia, reduced food intake, muscle catabolism, and insulin resistance, which are stimulating a catabolic state. Interesting recent data suggest that inflammation also modulates the response to nutritional treatment. Studies have demonstrated that patients with high inflammation show no response to nutritional interventions, while patients with lower levels of inflammation do. This may explain the contradictory results of nutritional trials to date. Several studies of heterogeneous patient populations, or in the critically ill or advanced cancer patients, have not found significant benefits on clinical outcome. Vice versa, several dietary patterns and nutrients with pro- or anti-inflammatory properties have been identified, demonstrating that nutrition influences inflammation. Within this review, we summarize and discuss recent advances in both the role of inflammation in malnutrition and the effect of nutrition on inflammation.

Indexed as

MalnutritionNeoplasmsAnorexiaHumansInflammationNutritional Statusclinical outcomesinflammationmalnutritionnutritional supportpersonalized nutritionprecision medicinescreening

Identifiers

PMID36904164
PMCPMC10005147
OpenAlexW4322502894

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read11
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.