Evidence map›Paper›PMID 36904150›Full record

ArticleNutrients2023

Risk Factors for Osteoporosis among Patients with Inflammatory Bowel Disease-Do We Already Know Everything?

Konrad Lewandowski, Magdalena Kaniewska, Martyna Więcek, Paulina Szwarc, Paulina Panufnik, Edyta Tulewicz-Marti, Magdalena Walicka, Edward Franek, Grażyna Rydzewska

Registry-linked trialFull text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06600334 (Prevalence of Osteoporosis Among Inflammatory Bowel Disease Patients in Assiut University Hospitals), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06600334 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Prevalence of Osteoporosis Among Inflammatory Bowel Disease Patients in Assiut University Hospitals

Typeobservational_patient_registrySponsorDina FathyRan2025 to 2026Enrolled55ConditionsOsteoporosisArmsdexa scan
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The association between theFrontiers in genetics · 2026
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Konrad LewandowskiClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0003-3866-4905
Magdalena KaniewskaClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.
Martyna WięcekClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0002-0413-8520
Paulina SzwarcClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.
Paulina PanufnikClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0003-0934-4590
Edyta Tulewicz-MartiClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0002-9301-9995
Magdalena WalickaDepartment of Internal Medicine, Endocrinology and Diabetology, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0001-8072-5279
Edward FranekDepartment of Internal Medicine, Endocrinology and Diabetology, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.
Grażyna RydzewskaClinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of the Inferior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0002-1267-7620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are many known risk factors for osteoporosis (OST) among patients with inflammatory bowel disease (IBD), one of which is physical activity. MATERIAL AND

methodsThe aim of the study is to assess the frequency and risk factors of OST among 232 patients with IBD compared to a group of 199 patients without IBD. The participants underwent dual-energy X-ray absorptiometry, laboratory tests, and completed a questionnaire about their physical activity.

resultsIt was found that 7.3% of IBD patients suffered from OST. Male gender, ulcerative colitis, extensive inflammation in the intestine, exacerbation of disease, rare physical activity, other forms of physical activity, past fractures, lower levels of osteocalcin, and higher levels of C-terminal telopeptide of type 1 collagen were risk factors for OST. As many as 70.6% of OST patients were rarely physically active.

conclusionsOST is a common problem in IBD patients. OST risk factors differ significantly between the general population and those with IBD. Modifiable factors can be influenced by patients and by physicians. The key to OST prophylaxis may be regular physical activity, which should be recommended in clinical remission. It may also prove valuable to use markers of bone turnover in diagnostics, which may enable decisions regarding therapy.

Indexed as

Crohn DiseaseInflammatory Bowel DiseasesOsteoporosisAbsorptiometry, PhotonBone DensityHumansMaleRisk Factorsinflammatory bowel diseasesmetabolic bone diseaseosteoporosisphysical activityvitamin D

Identifiers

PMID36904150
PMCPMC10005035

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.