Evidence map›Paper›PMID 36904078›Full record

ArticleNutrients2023

Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol-Feeding Mice.

Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning

Full text read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shengxiang YiSchool of Life Sciences, Nanchang University, Nanchang 330031, China.
Gaowei ZhangSchool of Life Sciences, Nanchang University, Nanchang 330031, China.
Mingyan LiuSchool of Life Sciences, Nanchang University, Nanchang 330031, China.
Wenjie YuSchool of Life Sciences, Nanchang University, Nanchang 330031, China.
Guohua ChengAgriculture and Rural Affairs Bureau of Nanfeng County, Fuzhou 344500, China.
Liping LuoSchool of Life Sciences, Nanchang University, Nanchang 330031, China.
Fangjian NingSchool of Life Sciences, Nanchang University, Nanchang 330031, China.

Funding

Jiangxi Agriculture Research System JXARS-14National Natural Science Foundation of China 32001779 and 21667018Research Project of State Key Laboratory of Food Science and Technology SKLF- ZZB-202123The Science and Technology Department of Jiangxi Province 20212AEI91010
6 · The paper itself

Abstract

Citrus honey (CH) is rich in nutrients that have a wide variety of biological functions, such as antibacterial, anti-inflammatory, and antioxidant activities, and which demonstrate therapeutic properties, such as anti-cancer and wound-healing abilities. However, the effects of CH on alcohol-related liver disease (ALD) and the intestinal microbiota remain unknown. This study aimed to determine the alleviating effects of CH on ALD and its regulatory effects on the gut microbiota in mice. In total, 26 metabolites were identified and quantified in CH, and the results suggested that the primary metabolites were abscisic acid, 3,4-dimethoxycinnamic acid, rutin, and two markers of CH, hesperetin and hesperidin. CH lowered the levels of aspartate aminotransferase, glutamate aminotransferase, and alcohol-induced hepatic edema. CH could promote the proliferation of Bacteroidetes while reducing the abundance of Firmicutes. Additionally, CH also showed some inhibitory effects on the growth of Campylobacterota and

Indexed as

CitrusDigestive System DiseasesGastrointestinal MicrobiomeHoneyLiver DiseasesAnimalsEthanolFatty Acids, VolatileMiceEthanolFatty Acids, Volatilealcohol–related liver diseasecitrus honeygut microbiotashort–chain fatty acids

Identifiers

PMID36904078
PMCPMC10005585

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read66
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.