Evidence map›Paper›PMID 36903831›Full record

ReviewNanomaterials (Basel, Switzerland)2023

BioMOF-Based Anti-Cancer Drug Delivery Systems.

Sandy Elmehrath, Ha L Nguyen, Sherif M Karam, Amr Amin, Yaser E Greish

Full text readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  15. Bioactive potency of extracts fromBiomedical reports · 2025
    Article
  16. Solid CaCOCurrent cancer drug targets · 2025
    Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandy ElmehrathDepartment of Chemistry, United Arab Emirates University, Al-Ain 15551, United Arab Emirates.ORCID 0000-0002-7446-7039
Ha L NguyenDepartment of Chemistry University of California-Berkeley, Kavli Energy Nanoscience Institute at UC Berkeley, and Berkeley Global Science Institute, Berkeley, CA 94720, USA.ORCID 0000-0002-4977-925X
Sherif M KaramDepartment of Anatomy, United Arab Emirates University, Al-Ain 15551, United Arab Emirates.ORCID 0000-0002-8590-3975
Amr AminZayed Centre for Health Sciences, United Arab Emirates University, Al-Ain 15551, United Arab Emirates.ORCID 0000-0001-8888-1102
Yaser E GreishDepartment of Chemistry, United Arab Emirates University, Al-Ain 15551, United Arab Emirates.ORCID 0000-0002-7147-6773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A variety of nanomaterials have been developed specifically for biomedical applications, such as drug delivery in cancer treatment. These materials involve both synthetic and natural nanoparticles and nanofibers of varying dimensions. The efficacy of a drug delivery system (DDS) depends on its biocompatibility, intrinsic high surface area, high interconnected porosity, and chemical functionality. Recent advances in metal-organic framework (MOF) nanostructures have led to the achievement of these desirable features. MOFs consist of metal ions and organic linkers that are assembled in different geometries and can be produced in 0, 1, 2, or 3 dimensions. The defining features of MOFs are their outstanding surface area, interconnected porosity, and variable chemical functionality, which enable an endless range of modalities for loading drugs into their hierarchical structures. MOFs, coupled with biocompatibility requisites, are now regarded as highly successful DDSs for the treatment of diverse diseases. This review aims to present the development and applications of DDSs based on chemically-functionalized MOF nanostructures in the context of cancer treatment. A concise overview of the structure, synthesis, and mode of action of MOF-DDS is provided.

Indexed as

BioMOFscancer treatmentchemical modificationdrug deliverymetal–organic frameworksnanostructures

Identifiers

PMID36903831
PMCPMC10005089

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read103
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.