Evidence map›Paper›PMID 36903683›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Automated Approach to In Vitro Image-Guided Photothermal Therapy with Top-Down and Bottom-Up-Synthesized Graphene Quantum Dots.

Bong Lee, Gretel A Stokes, Alina Valimukhametova, Steven Nguyen, Roberto Gonzalez-Rodriguez, Adam Bhaloo, Jeffery Coffer, Anton V Naumov

Full text read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Advances and Perspectives in Graphene-Based Quantum Dots Enabled Neuromorphic Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Holistic Investigation of Graphene Quantum Dot Endocytosis.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bong LeeDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.
Gretel A StokesDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.
Alina ValimukhametovaDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.
Steven NguyenDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.
Roberto Gonzalez-RodriguezDepartment of Physics, University of North Texas, Denton, TX 76203, USA.ORCID 0000-0001-6849-1799
Adam BhalooDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.
Jeffery CofferDepartment of Chemistry and Biochemistry, Texas Christian University, Fort Worth, TX 76109, USA.ORCID 0000-0003-0267-9646
Anton V NaumovDepartment of Physics and Astronomy, Texas Christian University, Fort Worth, TX 76109, USA.

Funding

Biocompatible Graphene Quantum Dots for Noninvasive Near-infrared BioimagingR15EB031528 · NIBIB · TEXAS CHRISTIAN UNIVERSITY · PI NAUMOV, ANTON, WORMLEY, FLOYD L. · 2021 to 2021
$410k
NIBIB NIH HHS R15 EB031528
6 · The paper itself

Abstract

Graphene-based materials have been the subject of interest for photothermal therapy due to their high light-to-heat conversion efficiency. Based on recent studies, graphene quantum dots (GQDs) are expected to possess advantageous photothermal properties and facilitate fluorescence image-tracking in the visible and near-infrared (NIR), while surpassing other graphene-based materials in their biocompatibility. Several GQD structures including reduced graphene quantum dots (RGQDs) derived from reduced graphene oxide via top-down oxidation and hyaluronic acid graphene quantum dots (HGQDs) hydrothermally bottom-up synthesized from molecular hyaluronic acid were employed to test these capabilities in the present work. These GQDs possess substantial NIR absorption and fluorescence throughout the visible and NIR beneficial for in vivo imaging while being biocompatible at up to 1.7 mg/mL concentrations. In aqueous suspensions, RGQDs and HGQDs irradiated with a low power (0.9 W/cm

Indexed as

fluorescence imaginggraphene quantum dotsnear-infrared fluorescencephotothermal therapy

Identifiers

PMID36903683
PMCPMC10005083

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.