Evidence map›Paper›PMID 36903662›Full record

ArticleMolecules (Basel, Switzerland)2023

Aspirin-Triggered Resolvin D1 (AT-RvD1) Protects Mouse Skin against UVB-Induced Inflammation and Oxidative Stress.

Cristina P B Melo, Priscila Saito, Renata M Martinez, Larissa Staurengo-Ferrari, Ingrid C Pinto, Camilla C A Rodrigues, Stephanie Badaro-Garcia, Josiane A Vignoli, Marcela M Baracat, Allan J C Bussmann and 3 more

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Dirhamnolipids fromACS omega · 2026
    Article
  3. Article
  4. Functional Characterization ofFoods (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cristina P B MeloDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.ORCID 0000-0003-1445-7637
Priscila SaitoDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Renata M MartinezDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Larissa Staurengo-FerrariDepartment of Pathology, Centre of Biological Sciences, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR445, Cx. Postal 10.011, Londrina 86057-970, PR, Brazil.
Ingrid C PintoDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Camilla C A RodriguesDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Stephanie Badaro-GarciaDepartment of Pathology, Centre of Biological Sciences, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR445, Cx. Postal 10.011, Londrina 86057-970, PR, Brazil.
Josiane A VignoliDepartment of Biochemistry and Biotechnology, Centre of Exact Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.
Marcela M BaracatDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Allan J C BussmannDepartment of Pathology, Centre of Biological Sciences, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR445, Cx. Postal 10.011, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-0807-4800
Sandra R GeorgettiDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.
Waldiceu A VerriDepartment of Pathology, Centre of Biological Sciences, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR445, Cx. Postal 10.011, Londrina 86057-970, PR, Brazil.ORCID 0000-0003-2756-9283
Rubia CasagrandeDepartment of Pharmaceutical Sciences, Centre of Health Science, Londrina State University, Londrina 86038-350, PR, Brazil.ORCID 0000-0002-2296-1668

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior finance code 001Fundação Araucária PPSUS grant agreement #041/2017; PRONEX grant agreement #014/2017; #PBA2022011000198National Council for Scientific and Technological Development #405027/2021-4; #427946/2018-2; #309633/2021-4; #307852/2019-9
6 · The paper itself

Abstract

Intense exposure to UVB radiation incites excessive production of reactive oxygen species (ROS) and inflammation. The resolution of inflammation is an active process orchestrated by a family of lipid molecules that includes AT-RvD1, a specialized proresolving lipid mediator (SPM). AT-RvD1 is derived from omega-3, which presents anti-inflammatory activity and reduces oxidative stress markers. The present work aims to investigate the protective effect of AT-RvD1 on UVB-induced inflammation and oxidative stress in hairless mice. Animals were first treated with 30, 100, and 300 pg/animal AT-RvD1 (i.v.) and then exposed to UVB (4.14 J/cm

Indexed as

AntioxidantsAspirinAnimalsDocosahexaenoic AcidsInflammationMiceNF-E2-Related Factor 2Oxidative StressUltraviolet RaysAntioxidantsAspirinDocosahexaenoic AcidsNF-E2-Related Factor 2resolvin D117(R)RvD1antioxidant capacityciclooxygenase-2cytokineslipid mediatorneutrophil infiltrationNrf2ROSsunburnultraviolet radiation

Identifiers

PMID36903662
PMCPMC10005614

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read34
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.