Evidence map›Paper›PMID 36903587›Full record

ArticleMolecules (Basel, Switzerland)2023

Superparamagnetic Iron-Oxide Nanoparticles Synthesized via Green Chemistry for the Potential Treatment of Breast Cancer.

Neha Tyagi, Priya Gupta, Zafar Khan, Yub Raj Neupane, Bharti Mangla, Nikita Mehra, Tanya Ralli, Abdulsalam Alhalmi, Asgar Ali, Omkulthom Al Kamaly and 3 more

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
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  8. Article
  9. Article
  10. Article
  11. Biological Activities of Natural Products III.Molecules (Basel, Switzerland) · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Neha TyagiDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Priya GuptaDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Zafar KhanDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Yub Raj NeupaneDepartment of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA 52242, USA.
Bharti ManglaDepartment of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi 110017, India.
Nikita MehraDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Tanya RalliDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.
Abdulsalam AlhalmiDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0001-7985-4241
Asgar AliDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0001-5476-3108
Omkulthom Al KamalyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-4706-4311
Asmaa SalehDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Fahd A NasrDepartment of Pharmacognosy, College of Pharmacy King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-6496-7822
Kanchan KohliDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.

Funding

Princess Nourah bint Abdulrahman University PNURSP2022R141
6 · The paper itself

Abstract

In the emerging field of nanomedicine, nanoparticles have been widely considered as drug carriers and are now used in various clinically approved products. Therefore, in this study, we synthesized superparamagnetic iron-oxide nanoparticles (SPIONs) via green chemistry, and the SPIONs were further coated with tamoxifen-conjugated bovine serum albumin (BSA-SPIONs-TMX). The BSA-SPIONs-TMX were within the nanometric hydrodynamic size (117 ± 4 nm), with a small poly dispersity index (0.28 ± 0.02) and zeta potential of -30.2 ± 0.09 mV. FTIR, DSC, X-RD, and elemental analysis confirmed that BSA-SPIONs-TMX were successfully prepared. The saturation magnetization (M

Indexed as

Magnetite NanoparticlesNanoparticlesNeoplasmsAnimalsDrug CarriersHumansIronMagnetic Iron Oxide NanoparticlesMCF-7 CellsOxidesRatsDrug CarriersIronMagnetite NanoparticlesOxidesbreast cancergreen chemistryserum albuminSPIONssuperparamagnetic iron-oxide nanoparticlestamoxifen

Identifiers

PMID36903587
PMCPMC10005561

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.