Evidence map›Paper›PMID 36903516›Full record

ArticleMolecules (Basel, Switzerland)2023

H-rGO-Pd NPs Nanozyme Enhanced Silver Deposition Strategy for Electrochemical Detection of Glypican-3.

Guiyin Li, Bo Wang, Ling Li, Xinhao Li, Ruijie Yan, Jintao Liang, Xinchun Zhou, Liuxun Li, Zhide Zhou

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Guiyin LiGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.ORCID 0000-0001-8356-4618
Bo WangGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Ling LiGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Xinhao LiGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Ruijie YanGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Jintao LiangGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Xinchun ZhouGuangdi Maoming Chemical Co., Ltd., Maoming High-Tech Industrial Development Zone, Maoming 525000, China.
Liuxun LiSolid Tumour Target Discovery Laboratory, Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0001-9762-4183
Zhide ZhouGuangxi Key Laboratory of Information Materials, School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
Guilin University of Electronic Technology · CNGuangdong University of Petrochemical Technology · CNNewcastle University · GB

Funding

Projects of Talents Recruitment of GDUPT RC-XJ2022000401the Fund of Guangxi Key laboratory of Metabolic Diseases Research No. 20-065-76the National Nature Science Foundation of China Nos. 62161009 and 62261010the Open Fund of Guangxi Key Laboratory of Information Materials No. 211022-K
6 · The paper itself

Abstract

Glypican-3 (GPC3), as an emerging biomarker, has been shown to be beneficial for the early diagnosis and treatment of hepatocellular carcinoma (HCC). In this study, an ultrasensitive electrochemical biosensor for GPC3 detection has been constructed based on the hemin-reduced graphene oxide-palladium nanoparticles (H-rGO-Pd NPs) nanozyme-enhanced silver deposition signal amplification strategy. When GPC3 specifically interacted with GPC3 antibody (GPC3

Indexed as

Biosensing TechniquesGlypicansGraphiteMetal NanoparticlesCarcinoma, HepatocellularElectrochemical TechniquesHeminHumansHydrogen PeroxideLiver NeoplasmsPalladiumSilverGlypicansGPC3 protein, humangraphene oxideGraphiteHeminHydrogen PeroxidePalladiumSilverelectrochemical nanobiosensorGlypican-3hepatocellular carcinomaH-rGO-Pd NPs nanozymeperoxidase-like catalytic silver deposition

Identifiers

PMID36903516
PMCPMC10004744
OpenAlexW4322743952

What OpenQuestion holds

Textfull text, public
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measurements read69
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.