Evidence map›Paper›PMID 36903426›Full record

ArticleMolecules (Basel, Switzerland)2023

Discovery of Flavone Derivatives Containing Carboxamide Fragments as Novel Antiviral Agents.

Bobo Zhao, Jiali Wang, Lu Wang, Ziwen Wang, Aidang Lu

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bobo ZhaoSchool of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300401, China.
Jiali WangSchool of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300401, China.
Lu WangSchool of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300401, China.
Ziwen WangTianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China.ORCID 0000-0001-9798-7021
Aidang LuSchool of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300401, China.ORCID 0000-0002-2255-8828

Funding

Hebei Natural Science Foundation B2020202028S&T Program of Hebei 21326504D
6 · The paper itself

Abstract

Plant virus diseases seriously affect the yield and quality of agricultural products, and their prevention and control are difficult. It is urgent to develop new and efficient antiviral agents. In this work, a series of flavone derivatives containing carboxamide fragments were designed, synthesized, and systematically evaluated for their antiviral activities against tobacco mosaic virus (TMV) on the basis of a structural-diversity-derivation strategy. All the target compounds were characterized by

Indexed as

FlavonesTobacco Mosaic VirusAntiviral AgentsDrug DesignMolecular Docking SimulationStructure-Activity RelationshipAntiviral AgentsFlavonesanti-TMV activitycarboxamide fragmentflavone derivativesmode of actionnatural product

Identifiers

PMID36903426
PMCPMC10004232

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read187
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.