Evidence map›Paper›PMID 36903408›Full record

ArticleMolecules (Basel, Switzerland)2023

Click-Functionalization of Silanized Carbon Nanotubes: From Inorganic Heterostructures to Biosensing Nanohybrids.

Gririraj Manoharan, Petra Bösel, Jannis Thien, Michael Holtmannspötter, Laura Meingast, Mercedes Schmidt, Henning Eickmeier, Markus Haase, Janina Maultzsch, Martin Steinhart and 3 more

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gririraj ManoharanDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.ORCID 0000-0002-5600-5199
Petra BöselDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.
Jannis ThienDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.ORCID 0000-0001-9304-3015
Michael HoltmannspötterCenter for Cellular Nanoanalytics, University of Osnabrück, 49076 Osnabrück, Germany.ORCID 0000-0003-2396-2627
Laura MeingastInstitute of Condensed Matter Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91058 Erlangen, Germany.
Mercedes SchmidtDepartment of Chemistry, University of Osnabrück, 49076 Osnabrück, Germany.
Henning EickmeierDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.
Markus HaaseDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.
Janina MaultzschInstitute of Condensed Matter Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91058 Erlangen, Germany.
Martin SteinhartDepartment of Chemistry, University of Osnabrück, 49076 Osnabrück, Germany.
Joachim WollschlägerDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.
Matteo PalmaDepartment of Chemistry, Queen Mary University of London, London E1 4NS, UK.
Carola MeyerDepartment of Physics, University of Osnabrück, 49076 Osnabrück, Germany.ORCID 0000-0003-0851-2767

Funding

Deutsche Forschungsgemeinschaft MA 4079/10-1Deutsche Forschungsgemeinschaft ME 3275/6- 1European Research Council ERC-2014-CoG 646742 INCANAUnited States Air Force Office of Scientific Research FA8655-21-1-7003
6 · The paper itself

Abstract

Here we present an approach to functionalize silanized single-walled carbon nanotubes (SWNTs) through copper-free click chemistry for the assembly of inorganic and biological nanohybrids. The nanotube functionalization route involves silanization and strain-promoted azide-alkyne cycloaddition reactions (SPACC). This was characterized by X-ray photoelectron spectroscopy, scanning electron microscopy, transmission electron microscopy, Raman spectroscopy and Fourier transform infra-red spectroscopy. Silane-azide-functionalized SWNTs were immobilized from solution onto patterned substrates through dielectrophoresis (DEP). We demonstrate the general applicability of our strategy for the functionalization of SWNTs with metal nanoparticles (gold nanoparticles), fluorescent dyes (Alexa Fluor 647) and biomolecules (aptamers). In this regard, dopamine-binding aptamers were conjugated to the functionalized SWNTs to perform real-time detection of dopamine at different concentrations. Additionally, the chemical route is shown to selectively functionalize individual nanotubes grown on the surface of silicon substrates, contributing towards future nano electronic device applications.

Indexed as

Metal NanoparticlesNanotubes, CarbonAzidesDopamineGoldAzidesDopamineGoldNanotubes, Carboncarbon nanotubesclick chemistryfunctionalizationnano biosensornanohybridssilanizationSPAAC

Identifiers

PMID36903408
PMCPMC10004328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.