Evidence map›Paper›PMID 36903405›Full record

ArticleMolecules (Basel, Switzerland)2023

Antitumor Effect of Chalcone Derivatives against Human Prostate (LNCaP and PC-3), Cervix HPV-Positive (HeLa) and Lymphocyte (Jurkat) Cell Lines and Their Effect on Macrophage Functions.

Bruno Horta, Joana Freitas-Silva, Jani Silva, Francisca Dias, Ana Luísa Teixeira, Rui Medeiros, Honorina Cidade, Madalena Pinto, Fátima Cerqueira

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. A Cyclam Salt as an Antifungal Agent: Interference withAntibiotics (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruno HortaMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.
Joana Freitas-SilvaInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.
Jani SilvaMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.
Francisca DiasMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0002-4993-4467
Ana Luísa TeixeiraMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0002-7489-2211
Rui MedeirosMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.ORCID 0000-0003-3010-8373
Honorina CidadeInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-0715-1779
Madalena PintoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-4676-1409
Fátima CerqueiraMolecular Oncology and Viral Pathology GRP-IC, Portuguese Institute of Oncology of Porto (IPO Porto), Rua António Bernardino de Almeida, 4200-072 Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chalcones are synthetic and naturally occurring compounds that have been widely investigated as anticancer agents. In this work, the effect of chalcones

Indexed as

ChalconeChalconesPapillomavirus InfectionsAnimalsCervix UteriFemaleHeLa CellsHumansInterleukin-10Interleukin-4Jurkat CellsLipopolysaccharidesMacrophagesMaleMiceProstateChalconeChalconesInterleukin-10Interleukin-4LipopolysaccharidesTransforming Growth Factor betaTumor Necrosis Factor-alphacancerchalconesimmunotherapytumor associated macrophages

Identifiers

PMID36903405
PMCPMC10004497

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.