Evidence map›Paper›PMID 36903375›Full record

ArticleMolecules (Basel, Switzerland)2023

OGT Binding Peptide-Tagged Strategy Increases Protein O-GlcNAcylation Level in

Yang Li, Zelan Yang, Jia Chen, Yihao Chen, Chengji Jiang, Tao Zhong, Yanting Su, Yi Liang, Hui Sun

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang LiCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Zelan YangCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Jia ChenCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Yihao ChenCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Chengji JiangCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Tao ZhongCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Yanting SuSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, Xianning 437100, China.
Yi LiangCollege of Life Sciences, Wuhan University, Wuhan 430072, China.
Hui SunCollege of Life Sciences, Wuhan University, Wuhan 430072, China.ORCID 0000-0001-9275-9257

Funding

National Natural Science Foundation of China 32000906, 31370849, 81670531, 32271326, 32071212
6 · The paper itself

Abstract

O-GlcNAcylation is a single glycosylation of GlcNAc mediated by OGT, which regulates the function of substrate proteins and is closely related to many diseases. However, a large number of O-GlcNAc-modified target proteins are costly, inefficient, and complicated to prepare. In this study, an OGT binding peptide (OBP)-tagged strategy for improving the proportion of O-GlcNAc modification was established successfully in

Indexed as

Escherichia coliEscherichia coli ProteinsAcetylglucosamineGlycosylationMethyltransferasesPeptidesProtein Processing, Post-Translationaltau ProteinsAcetylglucosamineEscherichia coli ProteinsMethyltransferasesOgt protein, E coliPeptidestau ProteinsOBP-tagged strategyO-GlcNAcOGTTau

Identifiers

PMID36903375
PMCPMC10004047

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.