Evidence map›Paper›PMID 36903355›Full record

ArticleMolecules (Basel, Switzerland)2023

To the Understanding of Catalysis by D-Amino Acid Transaminases: A Case Study of the Enzyme from

Sofia A Shilova, Maria G Khrenova, Ilya O Matyuta, Alena Y Nikolaeva, Tatiana V Rakitina, Natalia L Klyachko, Mikhail E Minyaev, Konstantin M Boyko, Vladimir O Popov, Ekaterina Yu Bezsudnova

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In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Effects of AddingAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofia A ShilovaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Maria G KhrenovaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0001-7117-3089
Ilya O MatyutaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-6297-8392
Alena Y NikolaevaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Tatiana V RakitinaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-3096-8659
Natalia L KlyachkoDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-9357-8236
Mikhail E MinyaevN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-4089-3697
Konstantin M BoykoBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0001-8229-189X
Vladimir O PopovBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Ekaterina Yu BezsudnovaBach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-4954-7547

Funding

Ministry of Science and Higher Education of the Russian Federation noRussian Science Foundation 19-14-00164the Grant of the President of the Russian Federation MD-1390.2022.1.4
6 · The paper itself

Abstract

Pyridoxal-5'-phosphate (PLP)-dependent transaminases are highly efficient biocatalysts for stereoselective amination. D-amino acid transaminases can catalyze stereoselective transamination producing optically pure D-amino acids. The knowledge of substrate binding mode and substrate differentiation mechanism in D-amino acid transaminases comes down to the analysis of the transaminase from

Indexed as

Amino AcidsTransaminasesBacillus subtilisBacteriaCatalysisGlutamic AcidKineticsPyridoxal PhosphateSubstrate SpecificityAmino AcidsGlutamic AcidPyridoxal PhosphateTransaminasesD-amino acidsenzymesstructuresubstrate-assisted catalysistransaminaseX-ray analysis

Identifiers

PMID36903355
PMCPMC10003956

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.