Evidence map›Paper›PMID 36903352›Full record

ReviewMolecules (Basel, Switzerland)2023

Green Chemistry Principles for Nano- and Micro-Sized Hydrogel Synthesis.

Sonia Trombino, Roberta Sole, Maria Luisa Di Gioia, Debora Procopio, Federica Curcio, Roberta Cassano

Full text readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Hydrogel-Based Continuum Soft Robots.Gels (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sonia TrombinoDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.ORCID 0000-0001-9939-4457
Roberta SoleDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.
Maria Luisa Di GioiaDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.
Debora ProcopioDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.ORCID 0000-0001-8071-0288
Federica CurcioDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.
Roberta CassanoDepartment of Pharmacy, Health and Nutritional Science, University of Calabria, 87036 Arcavacata, Italy.ORCID 0000-0001-6980-6799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing demand for drug carriers and green-technology-based tissue engineering materials has enabled the fabrication of different types of micro- and nano-assemblies. Hydrogels are a type of material that have been extensively investigated in recent decades. Their physical and chemical properties, such as hydrophilicity, resemblance to living systems, swelling ability and modifiability, make them suitable to be exploited for many pharmaceutical and bioengineering applications. This review deals with a brief account of green-manufactured hydrogels, their characteristics, preparations, importance in the field of green biomedical technology and their future perspectives. Only hydrogels based on biopolymers, and primarily on polysaccharides, are considered. Particular attention is given to the processes of extracting such biopolymers from natural sources and the various emerging problems for their processing, such as solubility. Hydrogels are catalogued according to the main biopolymer on which they are based and, for each type, the chemical reactions and the processes that enable their assembly are identified. The economic and environmental sustainability of these processes are commented on. The possibility of large-scale processing in the production of the investigated hydrogels are framed in the context of an economy aimed at waste reduction and resource recycling.

Indexed as

HydrogelsPolysaccharidesBiopolymersDrug CarriersTissue EngineeringBiopolymersDrug CarriersHydrogelsPolysaccharidesbiopolymersclick reactioncross-linkingdrug deliverygreen chemistryhydrogels

Identifiers

PMID36903352
PMCPMC10004334

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read27
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.