Evidence map›Paper›PMID 36903302›Full record

ArticleMolecules (Basel, Switzerland)2023

Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications.

Thibaut Barbier, Oana Dumitrescu, Gérard Lina, Yves Queneau, Laurent Soulère

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In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thibaut BarbierUniv Lyon, INSA Lyon, Université Claude Bernard Lyon 1, CNRS, CPE-Lyon, ICBMS, UMR 5246, Institut de Chimie et de Biochimie Moléculaires et Supramoléculaires, Bâtiment Lederer, 1 Rue Victor Grignard, 69622 Villeurbanne, France.ORCID 0000-0002-7979-4186
Oana DumitrescuHospices Civils de Lyon, Hôpital de la Croix Rousse-Centre de Biologie Nord, Laboratoire de Bactériologie, Institut des Agents Infectieux, Grande Rue de la Croix Rousse, 69004 Lyon, France.ORCID 0000-0001-8193-1437
Gérard LinaHospices Civils de Lyon, Hôpital de la Croix Rousse-Centre de Biologie Nord, Laboratoire de Bactériologie, Institut des Agents Infectieux, Grande Rue de la Croix Rousse, 69004 Lyon, France.ORCID 0000-0002-9236-7998
Yves QueneauUniv Lyon, INSA Lyon, Université Claude Bernard Lyon 1, CNRS, CPE-Lyon, ICBMS, UMR 5246, Institut de Chimie et de Biochimie Moléculaires et Supramoléculaires, Bâtiment Lederer, 1 Rue Victor Grignard, 69622 Villeurbanne, France.ORCID 0000-0003-4052-061X
Laurent SoulèreUniv Lyon, INSA Lyon, Université Claude Bernard Lyon 1, CNRS, CPE-Lyon, ICBMS, UMR 5246, Institut de Chimie et de Biochimie Moléculaires et Supramoléculaires, Bâtiment Lederer, 1 Rue Victor Grignard, 69622 Villeurbanne, France.ORCID 0000-0002-0488-550X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A conformational analysis and molecular docking study comparing 2,6-difluoro-3-methoxybenzamide (DFMBA) with 3-methoxybenzamide (3-MBA) has been undertaken for investigating the known increase of FtsZ inhibition related anti

Indexed as

Bacterial ProteinsBenzamidesMolecular ConformationMolecular Docking Simulation2,6-difluorobenzamide3-methoxybenzamideBacterial ProteinsBenzamides2,6-difluorobenzamideconformational analysisFtsZS. aureus

Identifiers

PMID36903302
PMCPMC10003973

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.