Evidence map›Paper›PMID 36903252›Full record

ArticleMolecules (Basel, Switzerland)2023

Taurocholic Acid and Glycocholic Acid Inhibit Inflammation and Activate Farnesoid X Receptor Expression in LPS-Stimulated Zebrafish and Macrophages.

Xutao Ge, Shaoze Huang, Can Ren, Lu Zhao

Full text read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. ReevaluatingWorld journal of gastroenterology · 2025
    Article
  16. Nettle (Frontiers in pharmacology · 2025
    Article
  17. Article
  18. Aqueous Extract ofFoods (Basel, Switzerland) · 2024
    Article
  19. Harnessing the power ofWorld journal of gastroenterology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xutao GePharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Xihu District, Hangzhou 310058, China.
Shaoze HuangDepartment of Medicine, Chiatai Qingchunbao Pharmaceutical Co., Ltd., Hangzhou 310023, China.
Can RenPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Xihu District, Hangzhou 310058, China.
Lu ZhaoPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Xihu District, Hangzhou 310058, China.

Funding

Zhejiang Provincial Natural Science Foundation LGF21H280005
6 · The paper itself

Abstract

A hyperactive immune response can be observed in patients with bacterial or viral infection, which may lead to the overproduction of proinflammatory cytokines, or "cytokine storm", and a poor clinical outcome. Extensive research efforts have been devoted to the discovery of effective immune modulators, yet the therapeutic options are still very limited. Here, we focused on the clinically indicated anti-inflammatory natural product

Indexed as

LipopolysaccharidesTaurocholic AcidAnimalsAnti-Inflammatory AgentsBile Acids and SaltsCytokinesGlycocholic AcidInflammationMacrophagesMiceZebrafishAnti-Inflammatory AgentsBile Acids and SaltsCytokinesGlycocholic AcidLipopolysaccharidesTaurocholic AcidCalculus bovisfarnesoid X receptorglycocholic acidtaurocholic acidzebrafish

Identifiers

PMID36903252
PMCPMC10003765

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measurements read43
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.