Evidence map›Paper›PMID 36902837›Full record

ArticleJournal of clinical medicine2023

The Short-Term Results of Autologous Platelet-Rich Plasma as an Adjuvant to Re-Intervention in the Treatment of Refractory Full-Thickness Macular Holes.

Matilde Buzzi, Guglielmo Parisi, Paola Marolo, Francesco Gelormini, Mariantonia Ferrara, Raffaele Raimondi, Davide Allegrini, Tommaso Rossi, Michele Reibaldi, Mario R Romano

Registry-linked trialFull text read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06323902 (Clinical Evidence of Autologous Platelet-Rich Plasma as a Treatment for Macular Holes), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06323902 completednot on this map

Clinical Evidence of Autologous Platelet-Rich Plasma as a Treatment for Macular Holes

TypeobservationalSponsorClinica Oftalmologica ParedesRan2022 to 2024Enrolled13ConditionsMacular Holes, Macular Hole of Left Eye (Disorder), Macular Hole of Right Eye (Disorder)ArmsPars plana vitrectomy, with or without epiretinal membrane peeling, plus PRGF membrane implantation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Optimal approaches for managing recurrent macular holes: a comprehensive systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Platelet concentrates in macular hole surgery. A journey through the labyrinth of terminology, preparation, and application: a comprehensive review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matilde BuzziDepartment of Biomedical Sciences, Humanitas University, 20090 Milan, Italy.
Guglielmo ParisiDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-0795-618X
Paola MaroloDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-8881-0926
Francesco GelorminiDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.
Mariantonia FerraraManchester Royal Eye Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.
Raffaele RaimondiEye Unit, Department of Ophthalmology, Humanitas Gavazzeni-Castelli, 24125 Bergamo, Italy.ORCID 0000-0001-8472-7984
Davide AllegriniEye Unit, Department of Ophthalmology, Humanitas Gavazzeni-Castelli, 24125 Bergamo, Italy.
Tommaso RossiIRCCS Fondazione Bietti ONLUS, 00198 Roma, Italy.
Michele ReibaldiDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-1368-6729
Mario R RomanoDepartment of Biomedical Sciences, Humanitas University, 20090 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the short-term efficacy and safety of autologous platelet-rich plasma (a-PRP) as an adjuvant to revisional vitrectomy for refractory full-thickness macular holes (rFTMHs). We conducted a prospective, non-randomized interventional study including patients with rFTMH after a pars plana vitrectomy (PPV) with internal limiting membrane peeling and gas tamponade. We included 28 eyes from 27 patients with rFTMHs: 12 rFTMHs in highly myopic eyes (axial length greater than 26.5 mm or a refractive error greater than -6D or both); 12 large rFTMHs (minimum hole width

Indexed as

autologous platelet-rich plasmahighly myopic full-thickness macular holesoptic disc pit maculopathypars plana vitrectomyrefractory full-thickness macular hole

Identifiers

PMID36902837
PMCPMC10004127

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read25
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.