Evidence map›Paper›PMID 36902816›Full record

ArticleJournal of clinical medicine2023

Optical Coherence Tomography: Retinal Imaging Contributes to the Understanding of Brain Pathology in Classical Galactosemia.

Amelie S Lotz-Havla, Tara Christmann, Klaus G Parhofer, Esther M Maier, Joachim Havla

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amelie S Lotz-HavlaDepartment of Inborn Errors of Metabolism, Dr. von Hauner Children's Hospital-University Hospital, LMU Munich, 80337 Munich, Germany.
Tara ChristmannInstitute of Clinical Neuroimmunology, University Hospital, LMU Munich, 81377 Munich, Germany.
Klaus G ParhoferMedical Department IV-Grosshadern, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0001-9873-0412
Esther M MaierDepartment of Inborn Errors of Metabolism, Dr. von Hauner Children's Hospital-University Hospital, LMU Munich, 80337 Munich, Germany.
Joachim HavlaInstitute of Clinical Neuroimmunology, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0002-4386-1340

Funding

LMU Munich Medical School doctoral fellowship
6 · The paper itself

Abstract

It remains unresolved whether central nervous system involvement in treated classical galactosemia (CG) is a progressive neurodegenerative process. This study aimed to investigate retinal neuroaxonal degeneration in CG as a surrogate of brain pathology. Global peripapillary retinal nerve fibre layer (GpRNFL) and combined ganglion cell and inner plexiform layer (GCIPL) were analysed in 11 CG patients and 60 controls (HC) using spectral-domain optical coherence tomography. Visual acuity (VA) and low-contrast VA (LCVA) were acquired to test visual function. GpRNFL and GCIPL did not differ between CG and HC (

Indexed as

brain damageclassical galactosemianeurodegenerationoptical coherence tomography (OCT)retinavisual acuity

Identifiers

PMID36902816
PMCPMC10004555

What OpenQuestion holds

Textfull text, public
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measurements read17
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.