Evidence map›Paper›PMID 36902767›Full record

ReviewJournal of clinical medicine2023

Autoimmune Hepatitis and Fibrosis.

Rinaldo Pellicano, Arianna Ferro, Francesca Cicerchia, Simone Mattivi, Sharmila Fagoonee, Marilena Durazzo

Full text readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Autoantibodies in the follow-up of autoimmune hepatitis.Journal of translational autoimmunity · 2026
    Review
  5. Article
  6. Review
  7. Fibrosis in Immune-Mediated and Autoimmune Disorders.Journal of clinical medicine · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Geographic Liver.Cureus · 2023
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rinaldo PellicanoUnit of Gastroenterology, Città della Salute e della Scienza Hospital, C.so Bramante 88, 10126 Turin, Italy.ORCID 0000-0003-3438-0649
Arianna FerroDepartment of Medical Sciences, University of Turin, C.so A.M. Dogliotti 14, 10126 Turin, Italy.
Francesca CicerchiaDepartment of Medical Sciences, University of Turin, C.so A.M. Dogliotti 14, 10126 Turin, Italy.
Simone MattiviDepartment of Medical Sciences, University of Turin, C.so A.M. Dogliotti 14, 10126 Turin, Italy.ORCID 0000-0002-5261-718X
Sharmila FagooneeInstitute for Biostructure and Bioimaging, National Research Council, Molecular Biotechnology Centre, 10126 Turin, Italy.ORCID 0000-0001-6070-6716
Marilena DurazzoDepartment of Medical Sciences, University of Turin, C.so A.M. Dogliotti 14, 10126 Turin, Italy.ORCID 0000-0003-2450-5911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune hepatitis (AIH) is a chronic immune-inflammatory disease of the liver, generally considered a rare condition. The clinical manifestation is extremely varied and can range from paucisymptomatic forms to severe hepatitis. Chronic liver damage causes activation of hepatic and inflammatory cells leading to inflammation and oxidative stress through the production of mediators. This results in increased collagen production and extracellular matrix deposition leading to fibrosis and even cirrhosis. The gold standard for the diagnosis of fibrosis is liver biopsy; however, there are serum biomarkers, scoring systems, and radiological methods useful for diagnosis and staging. The goal of AIH treatment is to suppress fibrotic and inflammatory activities in the liver to prevent disease progression and achieve complete remission. Therapy involves the use of classic steroidal anti-inflammatory drugs and immunosuppressants, but in recent years scientific research has focused on several new alternative drugs for AIH that will be discussed in the review.

Indexed as

autoimmune hepatitisliver diseasesliver fibrosis

Identifiers

PMID36902767
PMCPMC10004701

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.